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Using polyacrylamide\u2010sodium acetate (PAM\u2010NaAc) hydrogel as a model system, the crystallization of NaAc triggers the stretching and subsequent fracture of polymer chains, generating mechanoradicals at strain\u2010concentrated regions. These reactive species facilitate the incorporation of polymerizable compounds (monomers and crosslinkers). Specifically, localized polymerization of poly(ethylene glycol) diacrylate (PEGDA) monomers occurs at fracture sites, leading to covalent network integration and achieving a 51.5\u2010fold Young's modulus enhancement (from 0.024 to 1.24\u00a0MPa over 50 crystallization cycles). This crystallization\u2010induced self\u2010growth mechanism enables programmable topology engineering in soft matter systems, with implications for adaptive biomedical implants and fatigue\u2010resistant soft robots.<\/jats:p>","DOI":"10.1002\/smll.202500976","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T22:37:06Z","timestamp":1742596626000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Crystallization\u2010Induced Network Growth for Enhancing Hydrogel Mechanical Properties"],"prefix":"10.1002","volume":"21","author":[{"given":"Qianwei","family":"Liu","sequence":"first","affiliation":[{"name":"Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China Chengdu 611731 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhong","family":"Xiong","sequence":"additional","affiliation":[{"name":"Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China Chengdu 611731 China"},{"name":"Yangtze Delta Region Institute (Huzhou) University of Electronic Science and Technology of China Huzhou 313001 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanlai","family":"Fang","sequence":"additional","affiliation":[{"name":"Institute for Advanced Study Chengdu University Chengdu 610106 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2550-979X","authenticated-orcid":false,"given":"Jiaxi","family":"Cui","sequence":"additional","affiliation":[{"name":"Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China Chengdu 611731 China"},{"name":"Yangtze Delta Region Institute (Huzhou) University of Electronic Science and Technology of China Huzhou 313001 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,21]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202306565"},{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202206222"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-38768-z"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c23954"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1039\/D1PY00796C"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202403681"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-35555-0"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202210609"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202407125"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-34044-8"},{"key":"e_1_2_7_7_3","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-14807-x"},{"key":"e_1_2_7_7_4","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2402587121"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1TA08713D"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.31635\/ccschem.022.202201942"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aau9533"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/pol.1955.120188711"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja507983x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/C2SM27232F"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1039\/b924290b"},{"key":"e_1_2_7_12_1","author":"Liu Y. 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