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In contrast, 2D van der Waals (vdW) ferroelectrics feature inherently defect\u2010suppressed interfaces and weak interlayer coupling, mitigating charge trapping and defect accumulation. These attributes make them promising candidates for flexible and reconfigurable electronics, yet their long\u2010term mechanical endurance remains largely unexplored. Here, using atomic\u2010force\u2010microscopy\u2010based cyclic loading, we reveal that the ionic vdW ferroelectric CuInP\n                    <jats:sub>2<\/jats:sub>\n                    S\n                    <jats:sub>6<\/jats:sub>\n                    (CIPS) sustains stresses approaching 7\u00a0GPa for over 10\n                    <jats:sup>7<\/jats:sup>\n                    cycles \u2014exceeding all known ferroelectric counterparts. The fatigue process is dominated by stress\u2010induced flexoelectric fields that drive Cu\n                    <jats:sup>+<\/jats:sup>\n                    ions migration and local lattice disorder, which can be completely reversed by an external electric field to restore the crystal integrity. This field\u2010activated ionic rejuvenation extends the lifetime by an order of magnitude and introduces a new paradigm of fatigue engineering in ferroionic systems. Beyond revealing a self\u2010recoverable fatigue mechanism, our results establish design principles for durable, self\u2010healing, and reconfigurable 2D electromechanical and memory devices.\n                  <\/jats:p>","DOI":"10.1002\/smll.73338","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T12:42:43Z","timestamp":1775652163000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Rejuvenation of Mechanical Fatigue Resistance in 2D Ferroelectric CuInP\n                    <sub>2<\/sub>\n                    S\n                    <sub>6<\/sub>\n                    by Reversing Ionic Motion"],"prefix":"10.1002","volume":"22","author":[{"given":"Xiqi","family":"Wu","sequence":"first","affiliation":[{"name":"CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Modern Mechanics University of Science and Technology of China  Hefei P. R. 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