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Recent studies have extensively explored Ga\u2010containing radiopharmaceuticals, therapeutic compounds, and multifunctional formulations, clarifying their interactions with the tumor microenvironment and antitumor mechanisms. Clinically, Ga imaging agents, especially\n                    <jats:sup>68<\/jats:sup>\n                    Ga\u2010labeled probes, have become standard tools for precise diagnosis of prostate cancer, neuroendocrine tumors, and other malignancies, while Ga therapeutic agents act by interfering with DNA metabolism, regulating tumor immunity, and inhibiting angiogenesis. This review summarizes the current research status of Ga\u2010containing agents in tumor diagnosis and therapy, covering imaging\/therapeutic mechanisms and clinical applications, and clarifies their advantages and limitations. To promote their clinical translation, future efforts should focus on AI\u2010assisted multimodal imaging, personalized theranostics, intelligent targeted delivery systems and standardized multicenter clinical promotion.\n                  <\/jats:p>","DOI":"10.1002\/smll.73698","type":"journal-article","created":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T18:32:54Z","timestamp":1778437974000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Gallium\u2010Containing Agents for Tumor Diagnosis and Therapy: Current Status and Future Prospects"],"prefix":"10.1002","volume":"22","author":[{"given":"Yue","family":"Han","sequence":"first","affiliation":[{"name":"Department of Prosthodontics Peking University School and Hospital of Stomatology &amp; National Center for Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; National Engineering Research Center of Oral Biomaterials and Digital Medical Devices &amp; 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