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This design integrates the stability of solid substrates with the high adaptability of nanoparticles (NPs). The Ag\u2013Au BHC array provides a stable, ordered \u201chot spots\u201d framework, while Au NPs serve as \u201cenhancement units\u201d, establishing a dynamically coupled \u201cNPs\u2010BHC\u201d system. The substrate is capable of detecting Rhodamine 6G (R6G) at concentrations as low as 10\n                    <jats:sup>\u221214<\/jats:sup>\n                    M. When synergized with Au NPs, the detection limit further improves to 10\n                    <jats:sup>\u2212<\/jats:sup>\n                    <jats:sup>16<\/jats:sup>\n                    M, demonstrating extremely high detection sensitivity. The substrate maintains excellent signal stability and interference resistance when tilted and bent conditions. To enable rapid in situ detection, the SERS substrate was integrated with capillary glass tubing to create an integrated detection device. Capillary action facilitated rapid, power\u2010free sampling, enabling continuous dynamic monitoring of multiple target molecules at flow rates up to 1 mL\/s. This work not only provides a novel strategy for developing high\u2010performance, integrated bionic SERS sensing platforms but also offers an effective solution for the rapid, in situ, and dynamic detection of trace biomolecules in complex environments.\n                  <\/jats:p>","DOI":"10.1002\/smll.74078","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T09:30:03Z","timestamp":1782120603000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Capillary Integrated SERS System Inspired by Bee\u2010Hive Bionics: Enabling Dynamic Multi\u2010Component Detection of Trace Biomolecules"],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-4018-7059","authenticated-orcid":false,"given":"Enze","family":"Lv","sequence":"first","affiliation":[{"name":"Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology  Wuhan 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