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Herein, water\u2010dispersible and NIR\u2010responsive gold nanorod capsules (Au NrCs) are fabricated from mini\u2010gold nanorods (mini\u2010Au NRs) and small amphiphilic hexaethylene glycol (EG6) ligands via a solute\u2010induced phase separation strategy. Owing to their compact dimensions and tunable longitudinal localized surface plasmon resonance, the mini\u2010Au NRs enable assembly within sub\u2010200\u00a0nm nanocapsules while retaining NIR responsiveness. During capsule formation, nanoparticles and DNA cargoes are simultaneously encapsulated and concentrated within the capsules through liquid\u2010liquid phase separation, achieving approximately 90% DNA encapsulation efficiency and more than 1000\u2010fold enrichment. Furthermore, amino\u2010terminated EG6 ligands enable post\u2010assembly crosslinking of the Au NrCs with diepoxy\u2010polyethylene glycol, improving aqueous stability and dispersibility. The resulting Au NrCs exhibit efficient cargo release (&gt;95% within a few minutes) under low\u2010power 810\u00a0nm NIR LED irradiation through capsule disassembly, highlighting the potential of plasmonic nanocapsules for externally controlled delivery under relatively mild NIR LED irradiation conditions. These results establish a plasmonic nanocarrier platform integrating concentration\u2010assisted cargo encapsulation, enhanced aqueous stability, and controllable NIR\u2010triggered release, providing a basis for future drug delivery applications.<\/jats:p>","DOI":"10.1002\/smll.75754","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:07:34Z","timestamp":1790168854000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["NIR\u2010Responsive Gold Nanorod Capsules for Efficient Cargo Encapsulation and Release"],"prefix":"10.1002","author":[{"given":"Dongyu","family":"Zhang","sequence":"first","affiliation":[{"name":"Graduate School of Life Science Hokkaido University  Sapporo 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