{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T15:04:40Z","timestamp":1790348680359,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The scaling limitations of conventional transistors demand alternative device concepts capable of dynamic reconfigurability at the atomic scale. Resistive switching, a key mechanism for neuromorphic computing and non\u2010volatile memory, has been widely demonstrated in oxides, semiconductors, and nanocomposites, but not in pure one\u2010dimensional metallic systems. Here, we report the first electrical characterization of gold nanowires (AuNWs) synthesized within the lumen of functionalized microtubules. Structural analyses confirm continuous metallic AuNWs with local compositional inhomogeneities. Electrical measurements reveal three distinct conduction behaviors and abrupt resistance transitions under applied bias, consistent with electromigration driven by structural reorganization. Millisecond voltage pulsing enables active and reproducible modulation of resistance states without loss of metallic conduction, establishing a possible new multi\u2010state RS mechanism intrinsic to pure metallic nanowires. Owing to their high aspect ratio, lateral geometry, and CMOS\u2010compatible processing, microtubule\u2010templated AuNWs provide a versatile platform for reconfigurable interconnects.<\/jats:p>","DOI":"10.1002\/smll.75890","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T14:43:10Z","timestamp":1790347390000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multi\u2010State Resistance in Microtubule\u2010Templated Gold Nanowires"],"prefix":"10.1002","author":[{"given":"Borja","family":"Rodriguez\u2010Barea","sequence":"first","affiliation":[{"name":"Institute of Ion Beam Physics and Materials Research Helmholtz\u2010Zentrum Dresden\u2010Rossendorf  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1504-798X","authenticated-orcid":false,"given":"Brenda","family":"Palestina Romero","sequence":"additional","affiliation":[{"name":"B CUBE \u2013 Center for Molecular Bioengineering TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Kielar","sequence":"additional","affiliation":[{"name":"Institute of Ion Beam Physics and Materials Research Helmholtz\u2010Zentrum Dresden\u2010Rossendorf  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5200-6928","authenticated-orcid":false,"given":"Ren\u00e9","family":"H\u00fcbner","sequence":"additional","affiliation":[{"name":"Institute of Ion Beam Physics and Materials Research Helmholtz\u2010Zentrum Dresden\u2010Rossendorf  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0750-8515","authenticated-orcid":false,"given":"Stefan","family":"Diez","sequence":"additional","affiliation":[{"name":"B CUBE \u2013 Center for Molecular Bioengineering TUD Dresden University of Technology  Dresden Germany"},{"name":"Cluster of Excellence Physics of Life TUD Dresden University of Technology  Dresden Germany"},{"name":"Max Planck Institute of Molecular Cell Biology and Genetics  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6368-8728","authenticated-orcid":false,"given":"Artur","family":"Erbe","sequence":"additional","affiliation":[{"name":"Institute of Ion Beam Physics and Materials Research Helmholtz\u2010Zentrum Dresden\u2010Rossendorf  Dresden Germany"},{"name":"TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1109\/N\u2010SSC.2006.4785860"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","unstructured":"M.Horowitz \u201c1.1 Computing's 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