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Here, we report a metabolism\u2010regulated dynamic covalent double network living hydrogel that converts microbial D\u2010glucose consumption into programmable network reconstruction and morphomechanical transitions. The living hydrogel combines a permanent covalent network that maintains structural integrity and microbial confinement, and a phenylboronic acid\u2010poly (vinyl alcohol) dynamic network whose boronate ester equilibrium is regulated by D\u2010glucose. Exogenous D\u2010glucose competitively disrupts dynamic crosslinking, whereas microbial metabolism depletes D\u2010glucose and promotes reconstruction of the dynamic network. This glucose addition\u2010metabolism cycle enables reversible interfacial structural reconfiguration of living hydrogel modules, enhances bulk shrinkage, and converts chemical remodeling into bilayer bending actuation. The hydrogel supports diverse microorganisms, retains spatially confined populations, and undergoes repeated cycles of network reconstruction and mechanical actuation. By integrating actuation and genetically encoded sensing modules, we further construct a potentially recyclable living hydrogel device capable of sequential grasping and IPTG\u2010induced bacterial sensing. This work establishes metabolism\u2010regulated dynamic network reconstruction as a chemical strategy for coupling living biochemical processes with reversible morphology and mechanics in engineered living materials.<\/jats:p>","DOI":"10.1002\/smll.75932","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:45:25Z","timestamp":1790261125000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Metabolism\u2010Driven Morphomechanical Transitions in a Steady\u2010Dynamic Covalent Double Network Living Hydrogel"],"prefix":"10.1002","author":[{"given":"Junwei","family":"Hu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Materials\u2010Oriented Chemical Engineering, College of Chemical Engineering Nanjing Tech University  Nanjing People's Republic of 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