{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T16:46:25Z","timestamp":1791737185938,"version":"4.3.4"},"reference-count":68,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:00:00Z","timestamp":1791676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:00:00Z","timestamp":1791676800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100025294","name":"Research Ireland","doi-asserted-by":"publisher","award":["16\/IA\/4584 13\/IA\/1840"],"award-info":[{"award-number":["16\/IA\/4584 13\/IA\/1840"]}],"id":[{"id":"10.13039\/501100025294","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100025294","name":"Research Ireland","doi-asserted-by":"publisher","award":["13\/TIDA\/B2701"],"award-info":[{"award-number":["13\/TIDA\/B2701"]}],"id":[{"id":"10.13039\/501100025294","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001588","name":"Enterprise Ireland","doi-asserted-by":"publisher","award":["CF\u20102016\u20100389\u2010P"],"award-info":[{"award-number":["CF\u20102016\u20100389\u2010P"]}],"id":[{"id":"10.13039\/501100001588","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The ability to encode well\u2010defined physical properties and spatiotemporally controlled responses into multifunctional nanocomposites is enabling a new generation of advanced responsive systems. We describe the synthesis of magnetic nanoflowers (NFs) and their full dispersion in PEG\u2010based trimethylolpropane ethoxylate triacrylate (TET) to generate photo\u2010curable nanocomposites. NF\u2010loaded magnetic photocurable TET (Mol. Wt. 912\u00a0g\u00a0mol\n                    <jats:sup>\u22121<\/jats:sup>\n                    , NF\u2010TET912) is shown to provide full particle dispersion and hence crosslinked polymers with full retention of the AC\u2010field heating response. We demonstrate that these characteristics enable use of NF\u2010TET912 for biomedical applications as a versatile coating on glass, metal and plastics and for multiple 2D and 3D manufacturing techniques including templating, direct light processing (DLP) and direct laser writing using 2 photon polymerization (2PP). Nanocomposite structures, achieved using DLP, have demonstrated good fidelity to design, and provide targeted (5\u00b0C) AC\u2010field induced local temperature increases. Complex structures prepared using 2PP, have submicron feature size and resolution. The NF concentration range within which homogeneity and dispersion are possible is shown match the range needed for bio\u2010 applications and the materials exhibit no gross cellular toxicity. Finally, the potential of NF\u2010TET912 for AC\u2010field stimulated release of the antibiotic ciprofloxacin is evaluated.\n                  <\/jats:p>","DOI":"10.1002\/smll.76111","type":"journal-article","created":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T16:06:32Z","timestamp":1791734792000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multi\u2010Scale 3D Printing of Magnetic Polymer Nanocomposites with Controlled Particle Dispersion and Hyperthermic Response"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2685-4592","authenticated-orcid":false,"given":"Eoin P.","family":"McKiernan","sequence":"first","affiliation":[{"name":"School of Chemistry University College Dublin  Dublin 4 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6597-5242","authenticated-orcid":false,"given":"Jacek K.","family":"Wychowaniec","sequence":"additional","affiliation":[{"name":"School of Chemistry University College Dublin  Dublin 4 Ireland"},{"name":"AO Research Institute Davos  Davos Switzerland"},{"name":"SDU Biotechnology Department of Green Technology Faculty of Engineering and Danish Institute for Advanced Study (DIAS) University of Southern Denmark Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4753-4697","authenticated-orcid":false,"given":"Danielle","family":"Winning","sequence":"additional","affiliation":[{"name":"School of Chemistry University College Dublin  Dublin 4 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3493-0439","authenticated-orcid":false,"given":"Shane","family":"Clerkin","sequence":"additional","affiliation":[{"name":"School of Biomolecular and Biomedical Science University College Dublin  Dublin 4 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1673-5488","authenticated-orcid":false,"given":"Ines","family":"Martinez\u2010\u2010Chauvin","sequence":"additional","affiliation":[{"name":"School of Chemistry University College Dublin  Dublin 4 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Crean","sequence":"additional","affiliation":[{"name":"School of Biomolecular and Biomedical Science University College Dublin  Dublin 4 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5267-7780","authenticated-orcid":false,"given":"Alexa","family":"Ennis","sequence":"additional","affiliation":[{"name":"School of Chemistry &amp; AMBER the SFI Research Centre for Advanced Materials and BioEngineering Research Trinity College Dublin the University of Dublin  Dublin 2 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4397-0133","authenticated-orcid":false,"given":"Colm","family":"Delaney","sequence":"additional","affiliation":[{"name":"School of Chemistry &amp; AMBER the SFI Research Centre for Advanced Materials and BioEngineering Research Trinity College Dublin the University of Dublin  Dublin 2 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4704-2393","authenticated-orcid":false,"given":"Larisa","family":"Florea","sequence":"additional","affiliation":[{"name":"School of Chemistry &amp; AMBER the SFI Research Centre for Advanced Materials and BioEngineering Research Trinity College Dublin the University of Dublin  Dublin 2 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1270-8415","authenticated-orcid":false,"given":"Dermot F.","family":"Brougham","sequence":"additional","affiliation":[{"name":"School of Chemistry University College Dublin  Dublin 4 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202507559","article-title":"Stimuli\u2010Responsive Materials for Biomedical Applications","volume":"37","author":"Teixeira do Nascimento A.","year":"2025","journal-title":"Advanced Materials"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.8b00348"},{"key":"e_1_2_10_4_1","doi-asserted-by":"crossref","DOI":"10.1002\/adtp.201800092","article-title":"Externally Induced Drug Release Systems with Magnetic Nanoparticle Carriers: An Emerging Field in Nanomedicine","volume":"2","author":"Norris M. D.","year":"2018","journal-title":"Advanced Therapeutics"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.6b00131"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2024.01.030"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201400095"},{"key":"e_1_2_10_8_1","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202303861","article-title":"Magnetic Chitosan Bionanocomposite Films as a Versatile Platform for Biomedical Hyperthermia","volume":"13","author":"Barra A.","year":"2023","journal-title":"Advanced Healthcare Materials"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5RA22960J"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.8b00652"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/s22145132"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1779"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0NR01602K"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0185-0"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202505504"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202202278"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/smtd.202300414"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202004452"},{"key":"e_1_2_10_19_1","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.201804647","article-title":"A Stimuli\u2010Responsive Nanocomposite for 3D Anisotropic Cell\u2010Guidance and Magnetic Soft Robotics","volume":"29","author":"Tognato R.","year":"2018","journal-title":"Advanced Functional Materials"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/app13116844"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00170-024-14744-9"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep01652"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.1c00770"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.74149"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmmm.2018.09.111"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2020.112734"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcc.7b11255"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp3025478"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7TB02361H"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.08.033"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/gels8050297"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1109\/JMEMS.2020.3003628"},{"key":"e_1_2_10_33_1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3390\/mi11010017","article-title":"3D Printed Multi\u2010Functional Hydrogel Microneedles Based on High\u2010Precision Digital Light Processing","volume":"11","author":"Yao W.","year":"2020","journal-title":"Micromachines"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2018.03.031"},{"key":"e_1_2_10_35_1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3390\/molecules26010111","article-title":"Tailoring Atomoxetine Release Rate From DLP 3D\u2010Printed Tablets Using Artificial Neural Networks: Influence of Tablet Thickness and Drug Loading","volume":"26","author":"Stanojevi\u0107 G.","year":"2021","journal-title":"Molecules"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2019.05.008"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.2217\/3dp-2017-0009"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2019.03.047"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mattod.2018.04.001"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmacrolett.9b00196"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtla.2023.101700"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/app.53137"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202202539"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms9641"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202003725"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addma.2018.10.037"},{"key":"e_1_2_10_47_1","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202101048","article-title":"Facile Surface Functionalization Strategy for Two\u2010Photon Lithography Microstructures","volume":"17","author":"Zhang J.","year":"2021","journal-title":"Small"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/aisy.202000204"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202006341"},{"key":"e_1_2_10_50_1","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2018.00831","article-title":"Biologically Targeted Magnetic Hyperthermia: Potential and Limitations","volume":"9","author":"Chang D.","year":"2018","journal-title":"Frontiers in Pharmacology"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2009.10.041"},{"key":"e_1_2_10_52_1","first-page":"36185","article-title":"Thermoresponsiveness Across the Physiologically Accessible Range: Effect of Surfactant, Cross\u2010Linker, and Initiator Content on Size, Structure, and Transition Temperature of Poly(N\u2010isopropylmethacrylamide) Microgels","volume":"9","author":"Winning D.","year":"2024","journal-title":"ACS Omega"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcc.5b02555"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics12020124"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2025.123349"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jciso.2025.100142"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mseb.2025.118497"},{"key":"e_1_2_10_58_1","doi-asserted-by":"crossref","first-page":"8381","DOI":"10.1021\/ma0510136","article-title":"The Effect of Cross\u2010Linking on Gas Permeability in Cross\u2010Linked Poly","volume":"38","author":"Lin H.","year":"2005","journal-title":"Macromolecules"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/polb.20873"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201405757"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addma.2024.104443"},{"key":"e_1_2_10_62_1","doi-asserted-by":"crossref","DOI":"10.1080\/02656736.2025.2563301","article-title":"Alternating Magnetic Field and Induction Heating as Antibacterial Therapy in Implant\u2010associated Infections","volume":"42","author":"Irmak \u0160alandov\u00e1 M.","year":"2025","journal-title":"International Journal of Hyperthermia"},{"key":"e_1_2_10_63_1","doi-asserted-by":"crossref","DOI":"10.1080\/02656736.2023.2226845","article-title":"Mild Magnetic Hyperthermia Is Synergistic With an Antibiotic Treatment Against Dual Species Biofilms Consisting of S. aureus and P. aeruginosa by Enhancing Metabolic Activity","volume":"40","author":"Almutairi L. A.","year":"2023","journal-title":"International Journal of Hyperthermia"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5c14390"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.2c14752"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1021\/nl400188q"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5SU00701A"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13040556"},{"key":"e_1_2_10_69_1","doi-asserted-by":"crossref","DOI":"10.1002\/smll.201802278","article-title":"Size\u2010Controlled Nanoparticle Clusters of Narrow Size\u2010Polydispersity Formed Using Multiple Particle Types Through Competitive Stabilizer Desorption to a Liquid\u2013Liquid Interface","volume":"14","author":"Fox E. K.","year":"2018","journal-title":"Small"}],"container-title":["Small"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/smll.76111","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/smll.76111","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/smll.76111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T16:06:35Z","timestamp":1791734795000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/smll.76111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,11]]},"references-count":68,"alternative-id":["10.1002\/smll.76111"],"URL":"https:\/\/doi.org\/10.1002\/smll.76111","archive":["Portico"],"relation":{},"ISSN":["1613-6810","1613-6829"],"issn-type":[{"value":"1613-6810","type":"print"},{"value":"1613-6829","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,11]]},"assertion":[{"value":"2026-03-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e76111"}}