{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T08:55:23Z","timestamp":1791881723422,"version":"4.3.4"},"reference-count":48,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:00:00Z","timestamp":1791849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:00:00Z","timestamp":1791849600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["23XD1421800"],"award-info":[{"award-number":["23XD1421800"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018558","name":"Shanghai Shuguang Program","doi-asserted-by":"publisher","award":["21SG12"],"award-info":[{"award-number":["21SG12"]}],"id":[{"id":"10.13039\/501100018558","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The escalating threat of multidrug\u2010resistant (MDR) bacteria, especially methicillin\u2010resistant\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    (MRSA), urgently demands integrated multimodal therapies. However, it remains challenging to develop all\u2010in\u2010one platforms that synchronize photothermal therapy (PTT), photodynamic therapy (PDT), and ion release under a single near\u2010infrared (NIR) trigger. Herein, a van der Waals composite AgPor\/Hj, assembled from Ag(II) porphyrin and graphene\u2010TiO\n                    <jats:sub>2<\/jats:sub>\n                    heterojunction, is reported. Synergistic hot hole injection from the heterojunction to the porphyrin macrocycle greatly enhances NIR absorption, achieving an ultrahigh photothermal conversion efficiency of 64.5% for porphyrin\u2010based systems. Crucially, under a single 808\u00a0nm NIR irradiation, the engineered interface synchronizes PTT, PDT, and ultrafast Ag(II) release. This single\u2010NIR\u2010triggered triple\u2010modal synergy enables outstanding biofilm eradication and potent MRSA inhibition both in vitro and in vivo. AgPor\/Hj effectively eliminates bacteria in infected wounds and accelerates tissue repair, significantly outperforming vancomycin, the first\u2010line antibiotic for MRSA. Combined with excellent biocompatibility, low cost, and easy preparation, this synergistic platform provides a highly promising strategy for treating MDR bacterial wound infections.\n                  <\/jats:p>","DOI":"10.1002\/smll.76222","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T08:37:28Z","timestamp":1791880648000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Single\u2010NIR Triggered Triple\u2010Modal Therapy: Synergistic PTT\/PDT and Ultrafast Ag(II) Release via a Van Der Waals Silver Porphyrin\/Graphene\u2010TiO\n                    <sub>2<\/sub>\n                    Heterojunction for MRSA\u2010Infected Wounds"],"prefix":"10.1002","author":[{"given":"Yanling","family":"Lin","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering Shanghai Jiao Tong University  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1373-4447","authenticated-orcid":false,"given":"Weiyao","family":"Hu","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering Shanghai Jiao Tong University  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyuan","family":"Li","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering Shanghai Jiao Tong University  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1643-4631","authenticated-orcid":false,"given":"Xinhao","family":"Li","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering Shanghai Jiao Tong University  Shanghai People's Republic of 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