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As an emerging and rapidly evolving research direction, fully integrated wearable ultrasound platforms\u2014synergistically combining real\u2010time imaging, closed\u2010loop sensing, and on\u2010demand therapeutic intervention within a single conformal patch and system\u2014have been progressively utilized for chronic disease management and closed\u2010loop neuromodulation. This review summarizes and discusses the advanced wearable ultrasound technologies to provide insight into the underlying strategies that enable the convergence of diagnosis and therapy in diverse disease scenarios. This review primarily focuses on wearable ultrasound patches and systems for cardiovascular monitoring, musculoskeletal assessment, neurological treatment, sonodynamic therapy, drug delivery, and integrated theranostics. In addition, the challenges and development prospects of wearable ultrasound patches are analyzed to promote further clinical translation, with emphasis on the synergistic optimization of imaging and therapy, long\u2010term integration reliability, and fully integrated portable designs. It is earnestly expected that this kind of flexible\u2010electronics\u2010enabled wearable ultrasound technology will stimulate comprehensive investigation and promote the clinical development of next\u2010generation multifunctional theranostic platforms.<\/jats:p>","DOI":"10.1002\/smll.76233","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T08:39:52Z","timestamp":1791880792000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Recent Advances in Wearable Ultrasound Patches for Healthcare Applications"],"prefix":"10.1002","author":[{"given":"Faxing","family":"Zou","sequence":"first","affiliation":[{"name":"School of Life and Health Technology Dongguan University of Technology  Dongguan Guangdong China"},{"name":"The Institute for Advanced Study (IAS) Shenzhen University  Shenzhen Guangdong 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