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Abnormal changes in viscosity have been shown to be correlated with pathological activities and diseases of plants. However, current probes may not be suitable for sensing in plants due to their hydrophobicity and the phytochromes found in plants. With this research, we successfully constructed a structurally simple, water\u2010soluble near\u2010infrared fluorescent probe HJA\u2010MQ\u2010D, which can simultaneously monitor dynamic viscosity changes in plants and animal systems. The probe exhibits a relatively long emission wavelength (nearly 700\u00a0nm) and large Stokes shift (88\u00a0nm), and exceptional viscosity\u2010responsive performances with 140\u2010fold fluorescence intensity enhancement. More importantly, the HJA\u2010MQ\u2010D can image the viscosity fluctuation at the cellular level in plants (onion inner epidermis and mung bean sections) as well as at the whole\u2010plant level (mung bean and peanut seedling). In addition, HJA\u2010MQ\u2010D was used to monitor the viscosity changes in a nystatin\u2010induced zebrafish model. Based on these advanced characteristics, we anticipate that this probe will provide a powerful new tool for cross\u2010species viscosity monitoring.<\/jats:p>","DOI":"10.1002\/smo2.70043","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T15:21:02Z","timestamp":1773933662000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A novel water\u2010soluble near\u2010infrared fluorescent probe for monitoring viscosity fluctuations in plants and zebrafish under abiotic stresses"],"prefix":"10.1002","volume":"4","author":[{"given":"Yixue","family":"Feng","sequence":"first","affiliation":[{"name":"Key Laboratory of Chemo\/Biosensing and Detection of Xuchang Key Laboratory of Micro\u2010Nano Materials for Energy Storage and Conversion of Henan Province Henan Joint International Research Laboratory of Nanomaterials for Energy and Catalysis College of Chemical and Materials Engineering Xuchang 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