{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:55:13Z","timestamp":1786978513370,"version":"build-2736575974"},"reference-count":64,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Small Science"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:p>\n                    Biomaterials mimicking natural extracellular matrix are necessary to create an optimal microenvironment for cell adhesion, migration, proliferation, and differentiation. These scaffolds must possess bicontinuous interconnected porosity to ensure the effective exchange of oxygen, nutrients, and metabolic waste, which are crucial for developing functional tissues. Here, a novel bicontinuous interfacially jammed emulsion (\n                    <jats:styled-content>B<\/jats:styled-content>\n                    IJEL)\u2010\n                    <jats:styled-content>I<\/jats:styled-content>\n                    ntegrated\n                    <jats:styled-content>POR<\/jats:styled-content>\n                    ous\n                    <jats:styled-content>E<\/jats:styled-content>\n                    ngineered\n                    <jats:styled-content>S<\/jats:styled-content>\n                    ystem (BIPORES) is developed to confer bioinert synthetic polyethylene glycol diacrylate (PEGDA) with unique bicontinuous interconnected porosity and surface topography. This platform is\u00a0fabricated through controlled phase separation and interfacial stabilization of two continuous phases by nanoparticles. Functional validation using human mesenchymal stem cells, and human induced pluripotent stem cells\u2010derived cardiomyocytes and cardiac fibroblasts, reveals outstanding cell attachment, growth, proliferation, and\/or differentiation within tissue\u2010scale BIPORES scaffolds. These findings indicate that bicontinuous interconnected porosity with negative Gaussian curvature in the BIPORES scaffolds plays a key role in organ\u2010scale tissue engineering and regeneration.\n                  <\/jats:p>","DOI":"10.1002\/smsc.202500207","type":"journal-article","created":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:48:18Z","timestamp":1756374498000},"source":"Crossref","is-referenced-by-count":2,"title":["Bicontinuous Interconnected Porous Biomaterials for Tissue Engineering and Regeneration"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3022-0111","authenticated-orcid":false,"given":"Aihik","family":"Banerjee","sequence":"first","affiliation":[{"name":"Department of Bioengineering University of California, Riverside  Riverside CA 92521 United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjana","family":"Khanal","sequence":"additional","affiliation":[{"name":"Department of Chemical 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