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However, their inherently passive operation restricts practical applications, as they cannot precisely control particle position or dynamics inside the pore. Here, we introduce magnetic nanopore architectures that integrate a ferromagnetic layer into the nanopore system. Acting as a magnetic discontinuity within an otherwise uniformly magnetized film, the nanopore generates localized stray magnetic fields that enable magnetic tweezing of magnetic nanoparticles, which can be functionalized with fluorescent biomolecules. Importantly, the nanopore geometry is designed to reversibly switch between a nearly uniform magnetization state and a magnetic flux\u2010closure state through the application of momentary magnetic fields of predetermined amplitude. This capability allows the magnetic tweezing effect to be selectively activated or deactivated, enabling controlled capture and release of tagged biomolecules on demand. As a proof of concept, we demonstrate the selective magnetic trapping of fluorescent magnetic particles. Our work establishes a robust and controllable approach for reconfigurable, on\u2010chip magnetic nanopore platforms capable of selective trapping and high\u2010throughput single\u2010particle detection.<\/jats:p>","DOI":"10.1002\/smsc.70392","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:05:53Z","timestamp":1788861953000},"source":"Crossref","is-referenced-by-count":0,"title":["Reconfigurable Magnetic Nanopore Platform for Selective Trapping"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0572-3602","authenticated-orcid":false,"given":"Nageswar Reddy","family":"Sanamreddy","sequence":"first","affiliation":[{"name":"CIC nanoGUNE BRTA  Donostia\u2010San Sebastian Spain"},{"name":"Polymers and Advanced Materials: Physics, Chemistry and Technology University of the Basque Country (UPV\/EHU)  Donostia\u2010San Sebastian Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne","family":"Maunier","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ. 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