{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T10:49:32Z","timestamp":1789469372681,"version":"build-2803163510"},"reference-count":56,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32472277,32372320"],"award-info":[{"award-number":["32472277,32372320"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small Methods"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Establishing artificial photosynthesis systems in a simple but effective manner to mitigate the greenhouse effect and address the energy crisis remains challenging. The combination of photocatalysis technology with bioengineering is an emerging field with great potential to construct such artificial photosynthesis systems, but so far, it has barely been explored in this area. Herein, an artificial photocatalysis platform is constructed with high CO<jats:sub>2<\/jats:sub> conversion and H<jats:sub>2<\/jats:sub>O splitting capability by integration of CdS QDs into the intra\u2010subunit interface of H\u2010type ferritin (<jats:italic>Marsupenaeus japonicus<\/jats:italic>), a natural ferroxidase through protein interface redesign. The crystal structure of the synthesized CdS QDs with engineered ferritin molecules as bio\u2010templates confirmed the design at an atomic level. Notably, upon absorbing desirable visible light (\u2248420\u00a0nm), such a single CdS\u2010ferritin hybrid molecule is able to selectively catalyze the reduction of CO<jats:sub>2<\/jats:sub> into HCOOH (\u224890%), meanwhile catalyzing the oxidation of H<jats:sub>2<\/jats:sub>O into O<jats:sub>2<\/jats:sub> in an aqueous environment. The O<jats:sub>2<\/jats:sub> production rate reached to 180\u00a0\u00b5mol\u00a0g<jats:sup>\u22121<\/jats:sup>\u00a0h<jats:sup>\u22121<\/jats:sup>, and the HCOOH output hit almost 800\u00a0\u00b5mol\u00a0g<jats:sup>\u22121<\/jats:sup>\u00a0h<jats:sup>\u22121<\/jats:sup>. This work advances the utilization of the four\u2010helix bundle structure for crafting artificial photosynthesis systems, facilitating the seamless integration of bioengineering and photocatalysis technology.<\/jats:p>","DOI":"10.1002\/smtd.202400915","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T07:19:34Z","timestamp":1724915974000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Construction of An Artificial Photosynthesis System with A Single CdS QDs\u2010Ferritin Hybrid Molecule"],"prefix":"10.1002","volume":"9","author":[{"given":"Maoping","family":"Duan","sequence":"first","affiliation":[{"name":"College of Food Science and Nutritional Engineering China Agricultural University  Beijing 100083 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingjie","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Food Science and 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