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Here, bio\u2010functional porous chitosan scaffolds are developed by combining Ti\n                    <jats:sub>2<\/jats:sub>\n                    NT\n                    <jats:sub>x<\/jats:sub>\n                    MXene and carbon quantum dots (CQDs) for wound healing applications. Scaffold containing Ti\n                    <jats:sub>2<\/jats:sub>\n                    NT\n                    <jats:sub>x<\/jats:sub>\n                    and CQDs achieves 94.73% inhibition against\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    and 76.13% against\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    . Hemocompatibility assays showed low hemolysis rates (0.98% for CS\u2010CQDs\u2010MXene), well below the 5% ASTM threshold, indicating excellent blood compatibility. Cytocompatibility studies using L929 fibroblast cells demonstrated high cell viability (&gt;80%) and significant proliferation (125.58% at 72\u00a0h for CS\u2010CQDs\u2010MXene), with the scaffold promoting 46.32% wound closure in a 24\u2010h scratch assay, outperforming CS (27.08%) and CS\u2010CQDs (38.22%). CS\u2010CQDs\u2010MXene exhibited superior antioxidant activity across multiple assays, including\n                    <jats:italic>2,2 diphenyl\u20101\u2010picrylhydrazyl<\/jats:italic>\n                    (DPPH;39.5\u00a0mg TE\/g),\n                    <jats:italic>ferric reducing antioxidant power<\/jats:italic>\n                    (FRAP:43.8\u00a0mg TE\/g),\n                    <jats:italic>total antioxidant capacity<\/jats:italic>\n                    (TAC: 1.12\u00a0\u00b1\u00a00.08\u00a0mmol TE\/g), and\n                    <jats:italic>metal chelating activity<\/jats:italic>\n                    (MCA:17.76\u00a0\u00b1\u00a00.36\u00a0mg EDTAE\/g), indicating its capacity to scavenge free radicals and regulate redox balance in wound environments. These findings highlight the CS\u2010CQDs\u2010MXene scaffold as a promising multifunctional platform for wound healing, offering superior antibacterial activity, biocompatibility, and regenerative potential for advanced biomedical applications.\n                  <\/jats:p>","DOI":"10.1002\/smtd.202501415","type":"journal-article","created":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T05:40:28Z","timestamp":1761370828000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Ti\n                    <sub>2<\/sub>\n                    NT\n                    <sub>x<\/sub>\n                    MXene and Carbon Quantum Dots Modified Chitosan Scaffold for Potential Wound Healing: In Vitro Assessment of Cytotoxicity, Hemocompatibility, Antioxidant, and Antibacterial 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