{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T06:38:11Z","timestamp":1789195091297,"version":"build-2803163510"},"reference-count":85,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T00:00:00Z","timestamp":1767312000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T00:00:00Z","timestamp":1767312000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small Methods"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The conventional synthesis of acetophenone via the Friedel\u2010Crafts reaction is a highly waste\u2010intensive process. Consequently, the development of more sustainable and efficient alternatives is important. In this regard, radical oxidation represents a promising, environmentally benign route for acetophenone production. In this work, we designed a cobalt porphyrin\u2010based metalated porous organic polymer (\n                    <jats:bold>Co@POR\u2010POP<\/jats:bold>\n                    ), a highly active catalytic system, offering a potentially viable and cleaner approach to acetophenone production, utilizing styrene as the starting material. The catalyst exhibits a high surface area (BET = 650 m\n                    <jats:sup>2<\/jats:sup>\n                    g\n                    <jats:sup>\u22121<\/jats:sup>\n                    ) with bimodal pores, and delivers more than 90% yield of acetophenone under ambient conditions with excellent selectivity. Synchrotron\u2010based XAFS spectroscopy study revealed a square\u2010planar Co\u2010N\n                    <jats:sub>4<\/jats:sub>\n                    coordination environment with coordination number (CN) \u22484 and Co\u2500N bond distance of \u223c1.93 \u00c5, with no evidence of Co\u2013Co scattering, confirming the presence of isolated active sites. In situ EPR spectroscopy investigation displayed g\n                    <jats:sub>\u22a5<\/jats:sub>\n                    = 2.049 and g\n                    <jats:sub>\u2225<\/jats:sub>\n                    = 1.985 with hyperfine couplings A\n                    <jats:sub>\u22a5<\/jats:sub>\n                    = 49.8 MHz and A\n                    <jats:sub>\u2225<\/jats:sub>\n                    = 46.16 MHz, alongside an organic radical signal at g = 2.003. Spin\u2010trapping with DMPO detected both hydrogen (\u2022H) and styrene (\u2022C) radicals, validating a radical\u2010mediated mechanism. DFT calculations established a thermodynamically favourable pathway with an overall energy drop of \u22124.5 eV, supported by spin density localization at the Co centre and significant d\u2010\u03c0 orbital overlap facilitating O\n                    <jats:sub>2<\/jats:sub>\n                    activation. Overall, this work presents a new avenue of exploring novel organic transformation reactions using metalated porous organic polymer, opening scope for further investigations in this domain.\n                  <\/jats:p>","DOI":"10.1002\/smtd.202501981","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T11:25:34Z","timestamp":1767353134000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Navigating the Bio\u2010Inspired Structure\u2010Function Landscape: Spectroscopy Driven Finding of Hidden Radical Oxidation in Co\u2010porphyrinic Porous Organic Polymer"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4313-9331","authenticated-orcid":false,"given":"Bishal","family":"Boro","sequence":"first","affiliation":[{"name":"Department of Catalysis and Fine Chemicals CSIR\u2010Indian Institute of Chemical Technology  Uppal Road Hyderabad India"},{"name":"Academy of Scientific and Innovative Research (AcSIR)  Ghaziabad India"},{"name":"Organic &amp; Medicinal Chemistry Division CSIR\u2010Indian Institute of Chemical Biology  4\u2010Raja S. 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