{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T08:15:37Z","timestamp":1788509737415,"version":"build-2803163510"},"reference-count":189,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC 112\u20102628\u2010M\u2010001\u2010004\u2010MY3"],"award-info":[{"award-number":["NSTC 112\u20102628\u2010M\u2010001\u2010004\u2010MY3"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC 114\u20102113\u2010M\u2010001\u2010018\u2010"],"award-info":[{"award-number":["NSTC 114\u20102113\u2010M\u2010001\u2010018\u2010"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001869","name":"Academia Sinica","doi-asserted-by":"publisher","award":["AS\u2010GC\u2010111\u2010M03"],"award-info":[{"award-number":["AS\u2010GC\u2010111\u2010M03"]}],"id":[{"id":"10.13039\/501100001869","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001869","name":"Academia Sinica","doi-asserted-by":"publisher","award":["AS\u2010iMATE\u2010113\u201021"],"award-info":[{"award-number":["AS\u2010iMATE\u2010113\u201021"]}],"id":[{"id":"10.13039\/501100001869","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001869","name":"Academia Sinica","doi-asserted-by":"publisher","award":["AS\u2010PD\u20101142\u2010M06\u20102"],"award-info":[{"award-number":["AS\u2010PD\u20101142\u2010M06\u20102"]}],"id":[{"id":"10.13039\/501100001869","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small Methods"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Low\u2010input proteomics requires analytical strategies that can handle very small volumes while minimizing loss, dilution, and handling steps. Low\u2010voltage electrokinetic microfluidics offers a promising route to this goal by enabling controlled transport, separation, concentration, and droplet manipulation within compact chip\u2010based platforms. This review examines the integration of electrokinetic microfluidics with on\u2010chip electrospray ionization (ESI) for miniaturized protein analysis, with emphasis on how electric\u2010field\u2010driven sample handling can be combined with sensitive mass spectrometric detection. We discuss the fundamental electrokinetic mechanisms relevant to proteomic workflows, including electroosmotic flow (EOF), dielectrophoresis (DEP), electrowetting\u2010on\u2010dielectric (EWOD), electrohydrodynamic (EHD) flow, isotachophoresis (ITP), and electrothermal flow (ETF); and compare their operating conditions, strengths, and limitations for low\u2010input analysis. We also review recent advances in on\u2010chip ESI interfaces, emitter design, buffer management, and voltage\u2010domain separation, highlighting the technical factors that govern stable coupling between microfluidic manipulation and mass spectrometry (MS) detection. Finally, we outline future directions in materials, automation, and intelligent workflow control that may improve robustness and reproducibility in next\u2010generation electrokinetic proteomic platforms.<\/jats:p>","DOI":"10.1002\/smtd.70886","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T05:54:52Z","timestamp":1785131692000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Integrating Low\u2010Voltage Microfluidics With On\u2010Chip Electrospray Ionization for Miniaturized Protein Analysis"],"prefix":"10.1002","volume":"10","author":[{"given":"Noor Hidayat","family":"Abu Bakar","sequence":"first","affiliation":[{"name":"Institute of Chemistry Academia Sinica  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1125-1879","authenticated-orcid":false,"given":"Hsiung\u2010Lin","family":"Tu","sequence":"additional","affiliation":[{"name":"Institute of Chemistry Academia Sinica  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcpro.2025.101018"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2022.101556"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/prca.202400101"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/7651_2017_78"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2008.05.002"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41592\u2010023\u201001828\u20109"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.1c00321"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano11051118"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/gpbjnl\/qzaf012"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41592\u2010024\u201002558\u20102"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja0666295"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4RA05571C"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.202300056"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2007.11.119"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac0707986"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.1813"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2014.10.039"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0LC00936A"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216\u2010022\u201004043\u20101"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/mi17010071"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1039\/b503746h"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10404\u2010008\u20100399\u20109"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.202000313"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.202000213"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201900048"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/mi7090156"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00396\u2010006\u20101508\u20105"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/surfaces8030052"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.2c00734"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sna.2006.06.047"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200700725"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216\u2010018\u20101226\u20100"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-68424-6_10"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.70395"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.202300135"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2023.117080"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheatmasstransfer.2011.12.005"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheatmasstransfer.2004.02.020"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/la0301994"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2004.12.033"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201600296"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3LC00568B"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41378\u2010024\u201000750\u20100"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/bios14090417"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201100167"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2020.129204"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2024.135669"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.1c00083"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1039\/B306868B"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.4936300"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2024.135334"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1063\/5.0021177"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13206\u2010016\u20101208\u20102"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2023.115723"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.3c01098"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00640"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac500780w"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201300021"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021\u20109673(02)01246\u20103"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2020.122039"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010017\u201010579\u20105"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201200099"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201800162"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.3390\/mi10110762"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheatmasstransfer.2016.03.034"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010023\u201036502\u20109"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1109\/JPROC.2003.820535"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2011.12.052"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0507719102"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac800683s"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac103189p"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1039\/c0lc00490a"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2LC00688J"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M111.009407"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac701647s"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac401202c"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5b04912"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7LC01105A"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201700375"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5LC00523J"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.3390\/mi17040498"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tsep.2025.104087"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1308109110"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201200482"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.4155\/bio.14.306"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2020.08.049"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1039\/b601954d"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2011.09.074"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1039\/b110474h"},{"key":"e_1_2_10_91_1","doi-asserted-by":"publisher","DOI":"10.3390\/mi7040071"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4LC00592A"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.3390\/mi14020321"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.34133\/cbsystems.0091"},{"key":"e_1_2_10_95_1","unstructured":"T.Piasecki \u201cElectrohydrodynamic Focusing and Light Propagation in 2\u2010 Dimensional Microfluidic Devices for Preconcentration of Low Abundance Bioanalytes \u201d (Dublin City University 2012)."},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.1039\/B813639D"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1039\/b508224b"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.4907673"},{"key":"e_1_2_10_99_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.2734910"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2LC01147F"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.icheatmasstransfer.2010.11.004"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200900517"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac800428w"},{"key":"e_1_2_10_104_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac902218y"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac9902244"},{"key":"e_1_2_10_106_1","doi-asserted-by":"publisher","DOI":"10.1002\/jms.4955"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-8964-5_15"},{"key":"e_1_2_10_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijhydene.2023.04.333"},{"key":"e_1_2_10_109_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00677"},{"key":"e_1_2_10_110_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010017\u201017764\u20106"},{"key":"e_1_2_10_111_1","doi-asserted-by":"publisher","DOI":"10.1002\/celc.202200251"},{"key":"e_1_2_10_112_1","doi-asserted-by":"publisher","DOI":"10.3390\/bios14080374"},{"key":"e_1_2_10_113_1","doi-asserted-by":"publisher","DOI":"10.1039\/C2LC20799K"},{"key":"e_1_2_10_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2012.10.043"},{"key":"e_1_2_10_115_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac9509519"},{"key":"e_1_2_10_116_1","doi-asserted-by":"publisher","DOI":"10.1002\/mas.20248"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13361\u2010011\u20100251\u20104"},{"key":"e_1_2_10_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2022.339615"},{"key":"e_1_2_10_119_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13361\u2010017\u20101793\u2010x"},{"key":"e_1_2_10_120_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13361\u2010013\u20100749\u2010z"},{"key":"e_1_2_10_121_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4SC01700E"},{"key":"e_1_2_10_122_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c02323"},{"key":"e_1_2_10_123_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac049724"},{"key":"e_1_2_10_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasms.2010.02.003"},{"key":"e_1_2_10_125_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac5044016"},{"key":"e_1_2_10_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1044\u20100305(00)00163\u2010X"},{"key":"e_1_2_10_127_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.202100379"},{"key":"e_1_2_10_128_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac020396s"},{"key":"e_1_2_10_129_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5RA08490C"},{"key":"e_1_2_10_130_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac0346712"},{"key":"e_1_2_10_131_1","doi-asserted-by":"publisher","DOI":"10.1002\/mame.202200053"},{"key":"e_1_2_10_132_1","doi-asserted-by":"crossref","unstructured":"V.Miralles A.Huerre F.Malloggi andM.\u2010C. A.Jullien \u201cReview of Heating and Temperature Control in Microfluidic Systems: Techniques and Applications \u201d3 no.1(2013):33\u201367 https:\/\/doi.org\/10.3390\/diagnostics3010033.","DOI":"10.3390\/diagnostics3010033"},{"key":"e_1_2_10_133_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200700302"},{"key":"e_1_2_10_134_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar010110q"},{"key":"e_1_2_10_135_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2lc20982a"},{"key":"e_1_2_10_136_1","doi-asserted-by":"publisher","DOI":"10.1039\/b612140c"},{"key":"e_1_2_10_137_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6LC00163G"},{"key":"e_1_2_10_138_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010022\u201025831\u2010w"},{"key":"e_1_2_10_139_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13118"},{"key":"e_1_2_10_140_1","doi-asserted-by":"publisher","DOI":"10.1142\/S2339547817300013"},{"key":"e_1_2_10_141_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05058"},{"key":"e_1_2_10_142_1","doi-asserted-by":"publisher","DOI":"10.3390\/bios12070451"},{"key":"e_1_2_10_143_1","doi-asserted-by":"publisher","DOI":"10.1063\/5.0214436"},{"key":"e_1_2_10_144_1","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.R120.002234"},{"key":"e_1_2_10_145_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac200960h"},{"key":"e_1_2_10_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2017.12.046"},{"key":"e_1_2_10_147_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac202603s"},{"key":"e_1_2_10_148_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac101902c"},{"key":"e_1_2_10_149_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.7b01679"},{"key":"e_1_2_10_150_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac503014k"},{"key":"e_1_2_10_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2024.342998"},{"key":"e_1_2_10_152_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevFluids.6.123702"},{"key":"e_1_2_10_153_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac301332k"},{"key":"e_1_2_10_154_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c01651"},{"key":"e_1_2_10_155_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010019\u201013973\u2010x"},{"key":"e_1_2_10_156_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c02997"},{"key":"e_1_2_10_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1044\u20100305(03)00128\u20104"},{"key":"e_1_2_10_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasms.2005.06.011"},{"key":"e_1_2_10_159_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep38509"},{"key":"e_1_2_10_160_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.6b03422"},{"key":"e_1_2_10_161_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200410152"},{"key":"e_1_2_10_162_1","doi-asserted-by":"publisher","DOI":"10.1039\/c0an00253d"},{"key":"e_1_2_10_163_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac702354b"},{"key":"e_1_2_10_164_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010018\u201003367\u2010w"},{"key":"e_1_2_10_165_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1076996"},{"key":"e_1_2_10_166_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.5b02413"},{"key":"e_1_2_10_167_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021\u20109673(02)00345\u2010X"},{"key":"e_1_2_10_168_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5MD00617A"},{"key":"e_1_2_10_169_1","doi-asserted-by":"publisher","DOI":"10.1021\/jasms.3c00371"},{"key":"e_1_2_10_170_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.4998604"},{"key":"e_1_2_10_171_1","doi-asserted-by":"publisher","DOI":"10.1039\/b618901f"},{"key":"e_1_2_10_172_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.202200241"},{"key":"e_1_2_10_173_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.4c04532"},{"key":"e_1_2_10_174_1","doi-asserted-by":"publisher","DOI":"10.1039\/b600326e"},{"key":"e_1_2_10_175_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3SC00560G"},{"key":"e_1_2_10_176_1","doi-asserted-by":"publisher","DOI":"10.1002\/mas.21750"},{"key":"e_1_2_10_177_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201045659\u20104"},{"key":"e_1_2_10_178_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2LC01096H"},{"key":"e_1_2_10_179_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2SD00031H"},{"key":"e_1_2_10_180_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5LC00908A"},{"key":"e_1_2_10_181_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2LC00254J"},{"key":"e_1_2_10_182_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202510692"},{"key":"e_1_2_10_183_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.2c00124"},{"key":"e_1_2_10_184_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.2c00711"},{"key":"e_1_2_10_185_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4SC00839A"},{"key":"e_1_2_10_186_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmeasuresciau.3c00060"},{"key":"e_1_2_10_187_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.greeac.2025.100281"},{"key":"e_1_2_10_188_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac900522a"},{"key":"e_1_2_10_189_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4LC00872C"},{"key":"e_1_2_10_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2024.118004"}],"container-title":["Small Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/smtd.70886","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/smtd.70886","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/smtd.70886","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T07:36:32Z","timestamp":1788507392000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/smtd.70886"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,26]]},"references-count":189,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/smtd.70886"],"URL":"https:\/\/doi.org\/10.1002\/smtd.70886","archive":["Portico"],"relation":{},"ISSN":["2366-9608","2366-9608"],"issn-type":[{"value":"2366-9608","type":"print"},{"value":"2366-9608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,26]]},"assertion":[{"value":"2026-05-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70886"}}