{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:00:35Z","timestamp":1790172035156,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003245","name":"Ministerie van Onderwijs, Cultuur en Wetenschap","doi-asserted-by":"publisher","award":["1420578"],"award-info":[{"award-number":["1420578"]}],"id":[{"id":"10.13039\/501100003245","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small Methods"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A centrifugal emulsification platform enabling the parallel generation of emulsions directly in standard 96\u2010well plates is introduced. Upon centrifugation, the dispersed phase is driven through capillaries into the continuous phase, where step emulsification yields droplets by clean pinch\u2010off. The system achieves high reproducibility, with success rates above 90%. The platform's utility is demonstrated by screening silicone\u2010oil\/water emulsions across siloxane surfactants and NaCl gradients, and by mapping fluorinated emulsion stability as a function of salinity and the mixing ratio of two fluorinated surfactants of different chain lengths. In contrast to lab\u2010on\u2010a\u2010disc systems or single\u2010tube centrifugal devices, this approach combines minimal hardware requirements with high throughput and seamless compatibility with automated liquid\u2010handling and imaging workflows. Its simplicity and scalability make it suited for closed\u2010loop optimization, accelerating the discovery of sustainable non\u2010fluorinated droplet systems and enabling systematic studies of emulsion stability across diverse formulation\u00a0spaces.<\/jats:p>","DOI":"10.1002\/smtd.70983","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T03:14:34Z","timestamp":1787800474000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Centrifugal Step\u2010Emulsification Platform for High\u2010Throughput Emulsion Screening"],"prefix":"10.1002","volume":"10","author":[{"given":"Adam K.","family":"Kowalski","sequence":"first","affiliation":[{"name":"Institute for Molecules and Materials Radboud University Nijmegen the Netherlands"},{"name":"Institute of Physical Chemistry Polish Academy of Sciences Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aigars","family":"Piruska","sequence":"additional","affiliation":[{"name":"Institute for Molecules and Materials Radboud University Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Ho\u0142yst","sequence":"additional","affiliation":[{"name":"Institute of Physical Chemistry Polish Academy of Sciences Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4222-5411","authenticated-orcid":false,"given":"Wilhelm T. S.","family":"Huck","sequence":"additional","affiliation":[{"name":"Institute for Molecules and Materials Radboud University Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods11182883"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e32150"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S514928"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abl7160"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fochx.2025.102792"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1063\/5.0241903"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2024.140751"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12462-5"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4RA04298K"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8RA01254G"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2025.169512"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-021-16483-w"},{"key":"e_1_2_8_14_1","unstructured":"European Commission Commission Regulation (EU) 2024\/2462 of 19 September 2024 Amending Annex XVII to Regulation (EC) No 1907\/2006 as Regards Undecafluorohexanoic Acid (PFHxA) Its Salts and PFHxA\u2010related substances (EUR\u2010Lex 2024)."},{"key":"e_1_2_8_15_1","unstructured":"Environmental Protection Authority (New Zealand) EPA Bans \u2010Forever Chemicals' in Cosmetic Products (2024) https:\/\/www.epa.govt.nz\/news\u2010and\u2010alerts\/latest\u2010news\/epa\u2010bans\u2010forever\u2010chemicals\u2010in\u2010cosmetic\u2010products\/"},{"key":"e_1_2_8_16_1","unstructured":"Maine Legislature Title 38 \u00a71614: Products Containing PFAS(2024) https:\/\/legislature.maine.gov\/statutes\/38\/title38sec1614.html."},{"key":"e_1_2_8_17_1","unstructured":"California Air Resources Board AB 2771 \u2013 Ban on Perfluoroalkyl and Polyfluoroalkyl Substances in Cosmetic Products (PFAS\u2010Free Cosmetics Act)(2022)."},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfda.2016.10.021"},{"issue":"4","key":"e_1_2_8_19_1","first-page":"399","article-title":"Application of Turbiscan Lab to Study the Effect of Emulsifier Content on the Stability of Plant Origin Dispersion","volume":"40","author":"Zalewska A.","year":"2019","journal-title":"Chemical and Process Engineering: New Frontiers"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4CS00371C"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.9b01165"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiec.2020.08.025"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2019.03.036"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/mi13020171"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5SM00736D"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/macp.201600365"}],"container-title":["Small Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/smtd.70983","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/smtd.70983","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/smtd.70983","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:10:20Z","timestamp":1790169020000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/smtd.70983"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,26]]},"references-count":25,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/smtd.70983"],"URL":"https:\/\/doi.org\/10.1002\/smtd.70983","archive":["Portico"],"relation":{},"ISSN":["2366-9608","2366-9608"],"issn-type":[{"value":"2366-9608","type":"print"},{"value":"2366-9608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,26]]},"assertion":[{"value":"2026-02-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70983"}}