{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T11:44:45Z","timestamp":1792583085836,"version":"4.5.0"},"reference-count":45,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["202308320080"],"award-info":[{"award-number":["202308320080"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Small Methods"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The photothermal effect, which converts light into heat using nanosized light absorbers, has emerged as a powerful tool in energy conversion, cancer therapy and chemical transformation. Even if still debated, localized heating around nanoabsorbers under low\u2010intensity irradiation, conjugated with the molecular recognition abilities of monolayer protected nanoparticles, could enable the design of selective photothermal catalysts. Here, we report the development and application of thermolabile self\u2010cleaving molecular probes based on N\u2010benzyl\u2010N\u2010(2\u2010pyridyl)\u2010aminoethanol esters and carbonates to investigate localized photothermal effects. A series of derivatives with systematically varied substituents were synthesized and characterized, revealing that thermal reactivity can be finely tuned through electronic effects and solvent composition. Using fluorescence spectroscopy to monitor probe cleavage, we demonstrate that low\u2010intensity light irradiation (525\u00a0nm) induces reaction rates consistent with local temperature increases of 10\u00b0C\u201315\u00b0C above the bulk temperature. Crucially, the rate acceleration is observed only when the probes bind to the nanoparticle coating monolayer, as governed by electrostatic interactions. These results provide direct evidence for selective photothermal catalysis driven by molecular recognition, opening new perspectives for the design of smart photothermal nanozymes.<\/jats:p>","DOI":"10.1002\/smtd.71122","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T11:21:32Z","timestamp":1792581692000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Selective Photothermal Catalysis Enabled by Molecular Recognition on Ligand\u2010Protected Gold Nanoparticles"],"prefix":"10.1002","author":[{"given":"Fei","family":"Guo","sequence":"first","affiliation":[{"name":"Dipartimento Di Scienze Chimiche Universit\u00e0 di Padova  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Vicenzi","sequence":"additional","affiliation":[{"name":"Dipartimento Di Chimica \u201cGiacomo Ciamician\u201d Universit\u00e0 di Bologna  Bologna 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