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Nevertheless, such markers as carcinoembryonic antigen (CEA) and CA19\u20109 may have a role in pretherapeutic and post\u2010therapeutic monitoring of disease or recurrence. The newer tumor markers, including the carbohydrate markers, ornithine decarboxylase (ODC) and the polyamines, are of great interest as potential tumor markers; ODC and the polyamines may also have a future potential as therapeutic targets. However, further studies are needed to determine their true sensitivity and specificity in hereditary colonic neoplasia syndromes, as well as in patients without genetic syndromes who are at risk for colorectal cancer.<\/jats:p>","DOI":"10.1002\/ssu.2980030215","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T06:57:50Z","timestamp":1172127470000},"page":"126-132","source":"Crossref","is-referenced-by-count":7,"title":["Biochemical markers in patients with familial colonic neoplasia"],"prefix":"10.1002","volume":"3","author":[{"given":"Gordon D.","family":"Luk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann L.","family":"Silverman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis 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