{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T15:07:13Z","timestamp":1758121633450},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,8,18]],"date-time":"2006-08-18T00:00:00Z","timestamp":1155859200000},"content-version":"vor","delay-in-days":6438,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Surgical Oncology"],"published-print":{"date-parts":[[1989,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Endoscopic laser therapy for the palliation of malignant tumors of the gastrointestinal (GI) tract has rapidly gained widespread acceptance by the medical community. This form of therapy can offer significant tumor palliation in a relatively noninvasive manner to patients who have few other therapeutic options. Since its initial use for the treatment of esophageal cancer it has been extended to the treatment of a number of other GI, tract malignancies and has in fact been utilized for the palliation of intra\u2010 as well as extrahepatic bile duct tumors. A number of advances have occurred, including improvements in lasers and laser delivery systems, refinement of treatment techniques, development of new wavelengths, and refinement of drugs that allow more specific therapy of cancer. With continued laboratory and clinical investigations, laser therapy should realize its full potential, ultimately becoming a curative treatment modality that will offer patients benefits that are equal to or greater than more invasive and disfiguring surgery without its attendant morbidity and mortality.<\/jats:p>","DOI":"10.1002\/ssu.2980050105","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T05:59:44Z","timestamp":1172123984000},"page":"17-29","source":"Crossref","is-referenced-by-count":1,"title":["Laser therapy of cancer of the gastrointestinal and biliary tracts"],"prefix":"10.1002","volume":"5","author":[{"given":"Joseph J.","family":"Pietrafitta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,8,18]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(83)90014-8"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(84)90074-X"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1055\/s-2007-1018404","article-title":"Palliative laser therapy of malignant stenoses in the upper gastrointestinal tract","volume":"18","author":"Ell C","year":"1985","journal-title":"Endoscopy"},{"key":"e_1_2_1_5_2","first-page":"119","article-title":"Tumor irradiation by Nd:YAG laser of stenosing carcinomas and neoplastic sessile polyps in the upper and lower gastrointestinal tract","volume":"3","author":"Kiefhaber P","year":"1983","journal-title":"Lasers Surg Med"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900060509"},{"key":"e_1_2_1_7_2","first-page":"158","article-title":"New laser delivery system for the treatment of bile duct obstruction, (abstract)","volume":"33","author":"Pietrafitta JJ","year":"1987","journal-title":"Gastrointestinal Endosc."},{"key":"e_1_2_1_8_2","first-page":"75","article-title":"An overview of the clinical status of photodynamic therapy","volume":"170","author":"Dougherty TJ","year":"1984","journal-title":"Prog Clin Biol Res"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)60002-1"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800670602"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800670702"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19801115)46:10<2149::AID-CNCR2820461006>3.0.CO;2-W"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800691009"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930350303"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1986.01400040031003"},{"key":"e_1_2_1_16_2","first-page":"194","article-title":"Esophageal perforation complicating Nd:YAG laser treatment of esophageal neoplasms (abstract)","volume":"6","author":"Pietrafitta JJ","year":"1986","journal-title":"Lasers Surg Med"},{"key":"e_1_2_1_17_2","first-page":"109","article-title":"Esophageal dilatation\u2014Comparison of the savary\u2010guillard (S\u2010G) and the through the scope (TTS) balloon dilators in patients undergoing single session endoscopic laser therapy for malignant esophageal obstruction. 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