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The R classification reflects the effects of treatment and influences further treatment planning. Furthermore, the R classification is a strong predictor of prognosis. An acceptable long\u2010term prognosis can be expected only in R0 patients. Although there exist clear correlations between stage and R classification the differences in prognosis of R0 versus R1,2 cannot be explained by differences in stage alone. The prognostic significance of R classification is demonstrated by respective data for non\u2010small cell lung carcinoma, squamous cell carcinoma of oesophagus, gastric carcinoma, ductal adenocarcinoma of the pancreas, colorectal carcinoma, lung and liver metastases. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ssu.2980100105","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T04:15:35Z","timestamp":1172117735000},"page":"12-20","source":"Crossref","is-referenced-by-count":165,"title":["Residual tumor (R) classification and prognosis"],"prefix":"10.1002","volume":"10","author":[{"given":"Paul","family":"Hermanek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Wittekind","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,8,22]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"Manual for Staging of Cancer 1978","author":"American Joint Committee for Cancer Staging and End\u2010Results Reporting","year":"1978"},{"key":"e_1_2_1_3_2","volume-title":"Manual for Staging of Cancer","author":"American Joint Committee on Cancer","year":"1983"},{"key":"e_1_2_1_4_2","volume-title":"Manual for Staging on Cancer","author":"American Joint Committee on Cancer","year":"1988"},{"key":"e_1_2_1_5_2","volume-title":"TNM Classification of Malignant Tumours","author":"UICC","year":"1987"},{"key":"e_1_2_1_6_2","volume-title":"TNM Classification of Malignant Tumours","author":"UICC","year":"1992"},{"key":"e_1_2_1_7_2","volume-title":"Manual for Staging on Cancer","author":"American Joint Committee on Cancer","year":"1992"},{"key":"e_1_2_1_8_2","volume-title":"TNM Supplement 1993. 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