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In the current experiment, preweaning Sprague\u2010Dawley rats\u2014as a model of third trimester human exposure\u2014were administered the spin trapping agent, <jats:italic>N<\/jats:italic>\u2010tert\u2010butyl\u2010\u03b1\u2010phenylnitrone (PBN), daily prior to MA. Rats were given 0 (SAL) or 40 mg\/kg PBN prior to each MA dose (10 mg\/kg, 4\u00d7 per day) from postnatal day (P) 6\u201315. Littermates underwent Cincinnati water maze, Morris water maze, and radial water maze assessment beginning on P30 (males) or P60 (females). Males were also tested for conditioned contextual and cued freezing, while females were trained in passive avoidance. Findings show that, regardless of age\/sex, neonatal MA induced deficits in all tests, except passive avoidance. PBN did not ameliorate these effects, but had a few minor effects. 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