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Mating of the treated males with untreated females was induced seven days later by injection of human chorionic gonadotropic hormone (HCG). Accumulated lethality one week after fertilization among progeny was dose related. Morphological abnormalities among embryos that survived to hatching were similarly dose related. Because anatomically anomalous embryos may have impaired behavior, swimming capacity was tested, and anomalies in swimming behavior were also found to be dose related. Finally, short\u2010term cell cultures were made on minced embryos to obtain chromosome spreads. Structural aberrations, rings, dicentrics, etc of somatic chromosomes were also dose related.<\/jats:p>","DOI":"10.1002\/tcm.1770010305","type":"journal-article","created":{"date-parts":[[2006,2,3]],"date-time":"2006-02-03T21:50:52Z","timestamp":1139003452000},"page":"283-294","source":"Crossref","is-referenced-by-count":2,"title":["Dominant lethality in Xenopus laevis induced with triethylenemelamine (TEM)"],"prefix":"10.1002","volume":"1","author":[{"given":"Robert G.","family":"McKinnell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Betsy T.","family":"Kren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Bergad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Schultheis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Byrne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"IV","given":"J. 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PhD Thesis University of Minnesota."},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1093\/genetics\/77.4.753","article-title":"Effects of dose on the induction of dominant\u2010lethal mutations with triethylene\u2010melamine in male mice","volume":"77","author":"Matter BE","year":"1974","journal-title":"Genetics"},{"key":"e_1_2_1_15_1","volume-title":"Cloning: Nuclear Transplantation in Amphibia","author":"McKinnell RG","year":"1978"},{"key":"e_1_2_1_16_1","volume-title":"Cloning, A Biologist Reports","author":"McKinnell RG","year":"1979"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/63.3.821"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/em.2860010304"},{"key":"e_1_2_1_19_1","first-page":"251","volume-title":"Cloning: Nuclear Transplantation in Amphibia","author":"Nace GW","year":"1978"},{"key":"e_1_2_1_20_1","volume-title":"Normal Table of Xenopus laevis (Daudin)","author":"Nieuwkoop PD","year":"1967"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/10520297709116755"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0027-5107(77)90008-2"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-008X(77)80034-3"}],"container-title":["Teratogenesis, Carcinogenesis, and Mutagenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ftcm.1770010305","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/tcm.1770010305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T00:33:12Z","timestamp":1699057992000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/tcm.1770010305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,1]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1981,1]]}},"alternative-id":["10.1002\/tcm.1770010305"],"URL":"https:\/\/doi.org\/10.1002\/tcm.1770010305","archive":["Portico"],"relation":{},"ISSN":["0270-3211","1520-6866"],"issn-type":[{"value":"0270-3211","type":"print"},{"value":"1520-6866","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,1]]}}}