{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:10:00Z","timestamp":1760548200316},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2005,9,9]],"date-time":"2005-09-09T00:00:00Z","timestamp":1126224000000},"content-version":"vor","delay-in-days":7556,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Teratog Carcinog Mutagen"],"published-print":{"date-parts":[[1985,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The effects of different factors (temperature, light, enzymic activation) on the ability of selected mutagens and carcinogens to induce hereditary bleaching of <jats:italic>Euglena gracilis<\/jats:italic> were investigated. In the resting medium, the elevation of incubation temperature from 25\u00b0C to 37\u00b0C increased significantly the effect of all compounds tested on the frequency of bleached mutants of <jats:italic>E. gracilis.<\/jats:italic> The effect of light is not so unambiguous. While nitrosoguanidine (NG) exhibited practically the same bleaching activity both in the light and dark, the mutagenic effect of sodium azide (SA), nitrovin (NV), nitrosoethylurea (NEU), and benzo(a)pyrene (BP) was decreased in light. On the other hand, the light increased the bleaching activity of 5\u2010nitro\u20102\u2010furylacrylic acid (NFAA) significantly. The activation mixture S9 increased bleaching effect of NFAA and BP, whereas other mutagens were partially (NG and SA) or completely (NV and NEU) inactivated.<\/jats:p>","DOI":"10.1002\/tcm.1770050503","type":"journal-article","created":{"date-parts":[[2006,2,4]],"date-time":"2006-02-04T04:19:59Z","timestamp":1139026799000},"page":"329-337","source":"Crossref","is-referenced-by-count":12,"title":["Hyperthermia and other factors increasing sensitivity of <i>Euglena<\/i> to mutagens and carcinogens"],"prefix":"10.1002","volume":"5","author":[{"given":"Marian","family":"Ma\u010dor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Libor","family":"Ebringer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Siekel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,9,9]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.70.8.2281"},{"key":"e_1_2_1_3_2","volume-title":"Nitrofurans: Chemistry, Metabolism, Mutagenesis and Carcinogeneses","author":"Bryan GT","year":"1978"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00410835"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00602215"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-61-1-141"},{"key":"e_1_2_1_7_2","first-page":"579","article-title":"The action of rubiflavin and other cytostatic antibiotics on Euglena gracilils","volume":"19","author":"Ebringer L","year":"1972","journal-title":"Neoplasma"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-66856-2_6"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02896876"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00405768"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00410628"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.9.4.682"},{"key":"e_1_2_1_13_2","first-page":"1","article-title":"The photocatalytic breakage of nitrofurans and its consequences on Euglena gracilis","volume":"6","author":"Ebringer L","year":"1978","journal-title":"Acta FRN Univ Comen Microbiologia"},{"key":"e_1_2_1_14_2","first-page":"33","article-title":"The mutagenic action of 5\u2010nitrofuraldehyde on Mycobacterium phlei","volume":"7","author":"Ebringer L","year":"1979","journal-title":"Acta FRN Univ Comen Microbiologia"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02876691"},{"key":"e_1_2_1_16_2","first-page":"1","article-title":"Mutagenic action of nitrovin on Euglena gracilis and Salmonella typhimu\u2010 rium","volume":"10","author":"Ebringer L","year":"1982","journal-title":"Acta FRN Univ Comon Microbiologia"},{"issue":"11","key":"e_1_2_1_17_2","first-page":"1049","article-title":"The mutagenic effects of nitrovin","volume":"37","author":"Ebringer L","year":"1982","journal-title":"Biologia (Bratislava)"},{"key":"e_1_2_1_18_2","first-page":"675","article-title":"Mutagenic effects of two nitrofuran food preservatives","volume":"29","author":"Ebringer L","year":"1982","journal-title":"Neoplasma"},{"key":"e_1_2_1_19_2","first-page":"49","article-title":"A study of genetic activity of nitrofuran derivatives","volume":"11","author":"Ebringer L","year":"1984","journal-title":"Acta FRN Univ Comen Microbiologia"},{"key":"e_1_2_1_20_2","first-page":"119","article-title":"5\u2010Nitrofuryl acrylic acid\u2013A new conserving agent in vinification","volume":"84","author":"Farka\u0161 J","year":"1976","journal-title":"Chem Abstracts"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0027-5107(77)90174-9"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(62)90534-6"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(61)90328-6"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.137.3525.225"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.1965.tb01808.x"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.148.3669.497"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.1967.tb02031.x"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.1970.tb05171.x"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00337862"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01975115"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8137.1952.tb06116.x"},{"key":"e_1_2_1_32_2","unstructured":"ShorAL:Payzone\u2010Nitrovin a substance to improve weight gains. 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