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Cyclic 1,3\u2010diketones serve as versatile synthons and can be employed in one\u2010pot, single\u2010step reactions as well as in multistep sequences and multicomponent processes with a variety of reacting partners, including aldehydes, ketones, amines, isatins, and acenaphthoquinone. These transformations can be facilitated either by using stoichiometric amounts of reagents or under catalytic conditions, including nanoparticle\u2010supported systems, often resulting in significantly enhanced yields of the desired spirocycles. 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