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Information concerning the effects of gestational LD derives from case reports and series, epidemiologic studies, and experimental animal models. Although provocative, these studies fail to define a characteristic teratogenic effect. However, skin and cardiac involvement have predominated in some reports. Pregnancy wastage has been suggested primarily by animal studies. Gestational LD appears to be associated with a low risk of adverse pregnancy outcome, particularly with appropriated antibiotic therapy. Suggestions for management of clinical situations are presented. Teratology 64:276\u2013281, 2001. \u00a9 2001 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/tera.1074","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T21:20:09Z","timestamp":1030310409000},"page":"276-281","source":"Crossref","is-referenced-by-count":31,"title":["Teratogen update: Lyme disease"],"prefix":"10.1002","volume":"64","author":[{"given":"Daniel J.","family":"Elliott","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen C.","family":"Eppes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel D.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,10,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1128\/jcm.25.8.1564-1566.1987","article-title":"Seasonal prevalence of Borrelia burgdorferi in natural populations of white footed mice, Peromyscus leucopus","volume":"25","author":"Anderson JF","year":"1987","journal-title":"J Clin Microbiol"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1988.tb31857.x"},{"key":"e_1_2_1_4_1","unstructured":"BurgessEC Gendron\u2010FitzpatrickA MattisonM.1989.Foal mortality associated with natural infection of pregnant mares withBorrelia burgdorferi. 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