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The malformation rate was 13.23\/1000 total single births, and ranged from 8.66 to 20.27\/1000 births in the six hospitals. There also was significant interhospital variation in fetal death rate early neonatal death rate, and rate of multiple births. No significantly greater incidence of malformations in twins than nontwins was noted. Compared to other populations there were intermediate rates of anencephaly (1.17\/1000 births), low rates of spina bifida (0.16\/1000) and hydrocephalus (0.35\/1000), and high rates of cleft lip with or without cleft palate (1.92\/1000), radial polydactyly (1.02\/1000), osteogenesis imperfecta (0.16\/1000), and conjoined twins (1 in 6454 births). Methodological problems of incidence studies of congenital malformations are discussed.<\/jats:p>","DOI":"10.1002\/tera.1420050206","type":"journal-article","created":{"date-parts":[[2005,6,10]],"date-time":"2005-06-10T22:27:31Z","timestamp":1118442451000},"page":"159-169","source":"Crossref","is-referenced-by-count":57,"title":["The incidence of congenital malformations in a Chinese population: The Taipei collaborative study"],"prefix":"10.1002","volume":"5","author":[{"given":"Irvin","family":"Emanuel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih\u2010Wen","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura T.","family":"Gutman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fu\u2010Chi","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chia\u2010Chin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000129767"},{"key":"e_1_2_1_3_1","volume-title":"Congenital Malformations Surveillance, March, 1971","author":"Center for Disease Control","year":"1971"},{"key":"e_1_2_1_4_1","first-page":"44","article-title":"Racial nnd prenatal factors in major congenital malformations","volume":"20","author":"Chung C. 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