{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T13:44:12Z","timestamp":1756993452131},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,5,9]],"date-time":"2005-05-09T00:00:00Z","timestamp":1115596800000},"content-version":"vor","delay-in-days":12030,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Teratology"],"published-print":{"date-parts":[[1972,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In the years 1964\u201066, 338 newborns with a total of 379 gross malformations of the central nervous system and matched\u2010pair controls were reported to the Finnish Register of Congenital Malformations. Blood samples and detailed maternal histories were obtained from 162 mothers of defective children and their respective controls during the first 2, postpartum months. In the analysis of maternal antibodies the experimental group did not differ in most cases from the controls. However, antibodies against ECHO 7 occurred with significantly (P &lt; 0.005) higher frequency in the experimental group, and when high titers against ECHO 7 were compared this difference was even greater (P &lt; 0.001). On the other hand, antibodies against Coxsackie B1 and high titers against B5 occurred more frequently (P &lt; 0.05) in the control group.<\/jats:p>","DOI":"10.1002\/tera.1420050309","type":"journal-article","created":{"date-parts":[[2005,6,10]],"date-time":"2005-06-10T22:30:01Z","timestamp":1118442601000},"page":"345-351","source":"Crossref","is-referenced-by-count":6,"title":["Viral antibodies in mothers of defective children"],"prefix":"10.1002","volume":"5","author":[{"given":"Kaisa","family":"Lapinleimu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olli","family":"Koskimies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kari","family":"Cantell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauri","family":"Sax\u00e9n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,9]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"55","article-title":"Recent advances in the viral aetiology of congenital anomalies","volume":"1","author":"Brown G. C.","year":"1966","journal-title":"Adv. Terat."},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1970.10667251"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.199.3.183"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(63)91567-8"},{"key":"e_1_2_1_6_1","first-page":"167","article-title":"Asian influenza in pregnancy and congenital defects","volume":"14","author":"Doll R.","year":"1960","journal-title":"Br. J. Prev. Soc. Med."},{"key":"e_1_2_1_7_1","first-page":"749","article-title":"Congenital anomalies and virus infections","volume":"87","author":"Evans T. N.","year":"1963","journal-title":"Am. J. Obst. Gyn."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(65)90171-7"},{"key":"e_1_2_1_9_1","first-page":"52","volume-title":"3rd International Conference on Congenital Malformations","author":"Jones M. H.","year":"1969"},{"key":"e_1_2_1_10_1","first-page":"59","article-title":"The possible relationship of viruses, other than rubella and cytomegalo\u2010virus, to the etiology of birth defects","volume":"4","author":"Katz S. L.","year":"1968","journal-title":"Birth Defects Orig. Art. Ser."},{"key":"e_1_2_1_11_1","unstructured":"Klemetti A. andL.Sax\u00e9n1970The Finnish Register of Congenital Malformations. Organization and six years of experience. Health Services Research of the National Board of Health in Finland Publ. No. 9 Helsinki."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(70)80331-6"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(64)90837-3"},{"key":"e_1_2_1_14_1","volume-title":"Viral Infections of the Human Fetus","author":"Monif G. R. G.","year":"1969"},{"key":"e_1_2_1_15_1","first-page":"76","volume-title":"3rd International Conference on Congenital Malformations","author":"Rouquette C.","year":"1969"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1960.tb01121.x"},{"key":"e_1_2_1_17_1","volume-title":"Congenital Defects","author":"Sax\u00e9n L.","year":"1969"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.88.3.320"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.19.020168.002351"},{"key":"e_1_2_1_20_1","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1001\/jama.1966.03110090044013","article-title":"Low birth weight and maternal virus disease: a prospective study of rubella, mumps, chickenpox and hepatitis","volume":"197","author":"Siegal M.","year":"1966","journal-title":"J. Am. Med. Ass."},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.210.2.336"}],"container-title":["Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ftera.1420050309","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/tera.1420050309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T13:56:06Z","timestamp":1699797366000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/tera.1420050309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,6]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1972,6]]}},"alternative-id":["10.1002\/tera.1420050309"],"URL":"https:\/\/doi.org\/10.1002\/tera.1420050309","archive":["Portico"],"relation":{},"ISSN":["0040-3709","1096-9926"],"issn-type":[{"value":"0040-3709","type":"print"},{"value":"1096-9926","type":"electronic"}],"subject":[],"published":{"date-parts":[[1972,6]]}}}