{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T07:40:49Z","timestamp":1699774849893},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,5,10]],"date-time":"2005-05-10T00:00:00Z","timestamp":1115683200000},"content-version":"vor","delay-in-days":11483,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Teratology"],"published-print":{"date-parts":[[1973,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The cases of anencephaly and spina bifida occurring in the Collaborative Perinatal Study were analyzed for maternal and pediatric indices of intrauterine infections. As an extension of these studies epidemiological and clinical data from the study population were also analyzed. Review of data from serially collected maternal serum specimens for specific antibody to selected viral antigens as well as cord serum determinations of IgM provided no evidehce to suggest that perinatal infection plays a prominent role in the etiology of these malformations. The raciai distributions of anencephaly and spina bifida differed significantly in that the rate of anencephaly was six times higher in whites than blacks. On the other hand whites and blacks had approximately the same rates of spina bifida. In view of this raciai disparity the Suggestion that a single common environmental agent is responsible for both defects, as included in Renwick's ('72) hypothesis must be modified.<\/jats:p>","DOI":"10.1002\/tera.1420080319","type":"journal-article","created":{"date-parts":[[2005,6,10]],"date-time":"2005-06-10T22:38:22Z","timestamp":1118443102000},"page":"359-361","source":"Crossref","is-referenced-by-count":4,"title":["Perinatal infections and epidemiology of anencephaly and spina bifida"],"prefix":"10.1002","volume":"8","author":[{"given":"Jerome E.","family":"Kurent","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John L.","family":"Sever","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,10]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"44","article-title":"Racial and prenatal factors in congenital malformations","volume":"20","author":"Chung C. S.","year":"1968","journal-title":"Am. J. Hum. Genet"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(59)91585-5"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1969.00480080015001"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(69)92371-X"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1093\/oxfordjournals.aje.a121400","article-title":"Anencephaly and maternal age","volume":"95","author":"Janerich D. T.","year":"1972","journal-title":"Am. J. Epid."},{"key":"e_1_2_1_7_1","first-page":"169","volume-title":"Epidemiology of Neurologic and Sense Organs Disorders","author":"Kurtzke J. F.","year":"1973"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(71)80026-0"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00122075"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196711232772104"},{"key":"e_1_2_1_11_1","first-page":"67","article-title":"Hypothesis. Anencephaly and spina bifida are usually preventable by avoidance of a specific but unidentified substance present in certain potato tubers","volume":"26","author":"Renwick J. H.","year":"1972","journal-title":"Br. J Prev. Soc. Med."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(69)80365-3"}],"container-title":["Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ftera.1420080319","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/tera.1420080319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T07:22:11Z","timestamp":1699773731000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/tera.1420080319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,12]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1973,12]]}},"alternative-id":["10.1002\/tera.1420080319"],"URL":"https:\/\/doi.org\/10.1002\/tera.1420080319","archive":["Portico"],"relation":{},"ISSN":["0040-3709","1096-9926"],"issn-type":[{"value":"0040-3709","type":"print"},{"value":"1096-9926","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,12]]}}}