{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T15:20:57Z","timestamp":1790004057820,"version":"4.0.1"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,5,10]],"date-time":"2005-05-10T00:00:00Z","timestamp":1115683200000},"content-version":"vor","delay-in-days":11421,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Teratology"],"published-print":{"date-parts":[[1974,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The use of 6168 unselected malformed infants, obtained from the Swedish Register of Congenital Malformations during the years 1965\u20131971, made possible an analysis of a complex of malformations that form a series from the Potter syndrome to sirenomelia. A total of 73 infants belonging to this group were identified among the approximately 550,000 births \u2014 an incidence of 1\/7500 births. They formed a series from infants with the typical Potter syndrome to typical sirenomelia. Analysis of the association of various malformations indicated til at pulmonary hypoplasia and \u201cPotter face\u201d are not only an effect of oligohydram\u2010nios. A mesodermal damage is postulated as the cause of the complex of malformations. A variable craniocaudal extension of the damage can explain the different expressions of the syndrome. Closure defects of the central nervous system, facial clefts, and congenital heart defects were less common than expected when compared with other infants with multiple malformations. The incidence of these infants born in Sweden has apparently increased over the years. There was also an apparent preponderance of them in central Sweden. Pregnancies ending with the birth of infants with this malformation complex began during summertime more often than could be expected. No exogenous cause was identified.<\/jats:p>","DOI":"10.1002\/tera.1420090113","type":"journal-article","created":{"date-parts":[[2005,6,10]],"date-time":"2005-06-10T22:44:47Z","timestamp":1118443487000},"page":"99-111","source":"Crossref","is-referenced-by-count":73,"title":["Caudal mesoderm pattern of anomalies: From renal agenesis to sirenomelia"],"prefix":"10.1002","volume":"9","author":[{"given":"Bengt","family":"K\u00e4ll\u00e9n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Winberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,5,10]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5176.841"},{"key":"e_1_2_1_3_1","volume-title":"Applied General Statistics","author":"Croxton F. E.","year":"1946"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.36.186.152"},{"key":"e_1_2_1_5_1","first-page":"653","article-title":"The pathogenesis of Potter's syndrome of renal agenesis","volume":"107","author":"Fitch N.","year":"1972","journal-title":"Can. Med. J."},{"key":"e_1_2_1_6_1","first-page":"765","article-title":"A Swedish register of congenital malformations. Experience with continuous registration during 2 years with special reference to multiple malformations","volume":"41","author":"K\u00e4ll\u00e9n B.","year":"1968","journal-title":"Pediatrics"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1542\/peds.44.3.410","article-title":"Multiple malformations studied with a national register of malformations","volume":"44","author":"K\u00e4ll\u00e9n B.","year":"1969","journal-title":"Pediatrics"},{"key":"e_1_2_1_8_1","unstructured":"K\u00e4ll\u00e9n B. andJ.Winberg1971The Swedish register of congenital malformations 1964\u20101969. The Swedish Board of Health and Welfare Reports. Series: Patient Statistics number 7."},{"key":"e_1_2_1_9_1","first-page":"123","volume-title":"Supplement to Teratology Workshop Manual. A collection of lectures and demonstrations from the Second Workshop in Teratology","author":"Kalter H.","year":"1965"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(68)80440-8"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00523644"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.37.4.672"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(46)80241-5"},{"key":"e_1_2_1_14_1","first-page":"3","article-title":"Bilateral absence of ureters and kidneys. A report of 50 cases","volume":"25","author":"Potter E. L.","year":"1965","journal-title":"Obst Gyn."},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1970.00480270022004"},{"key":"e_1_2_1_16_1","volume-title":"Recognizable Patterns of Human Malformation. Genetic, embryologic, and clinical aspects","author":"Smith D. W.","year":"1970"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00438459"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00436763"}],"container-title":["Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ftera.1420090113","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/tera.1420090113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T12:11:00Z","timestamp":1699791060000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/tera.1420090113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,2]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1974,2]]}},"alternative-id":["10.1002\/tera.1420090113"],"URL":"https:\/\/doi.org\/10.1002\/tera.1420090113","archive":["Portico"],"relation":{},"ISSN":["0040-3709","1096-9926"],"issn-type":[{"value":"0040-3709","type":"print"},{"value":"1096-9926","type":"electronic"}],"subject":[],"published":{"date-parts":[[1974,2]]}}}