{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T15:14:05Z","timestamp":1764688445854},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,5,16]],"date-time":"2005-05-16T00:00:00Z","timestamp":1116201600000},"content-version":"vor","delay-in-days":10759,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Teratology"],"published-print":{"date-parts":[[1975,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The effect of dietary deficiency during pregnancy of zinc or magnesium on maternal and fetal chromosomes was studied. Pregnant rats were given a zinc\u2010deficient or a magnesium\u2010deficient diet from the beginning of pregnancy and maternal bone marrow and fetal liver were removed on day 19 of gestation. Chromosome spreads were prepared and rnetaphases examined for abnormalities, Both magnesium\u2010 and zinc\u2010deficient maternal bone\u2010marrow and fetal liver cells showed significantly more chromosomal abnormalities than did those of controls. The chromosomal aberrations occurring in highest incidence in magnesium\u2010deficient animals were terminal deletions and fragments. A higher than normal incidence of \u201cstickiness\u201d was also observed in cells from magnesium\u2010deficient animals. In zinc\u2010deficient animals, on the other hand, the chromosomal aberrations with the highest incidence were gaps and terminal deletions.<\/jats:p>","DOI":"10.1002\/tera.1420120302","type":"journal-article","created":{"date-parts":[[2005,6,10]],"date-time":"2005-06-10T22:51:43Z","timestamp":1118443903000},"page":"221-226","source":"Crossref","is-referenced-by-count":44,"title":["Chromosomal abnormalities in maternal and fetal tissues of magnesium\u2010 or zinc\u2010deficient rats"],"prefix":"10.1002","volume":"12","author":[{"given":"Linda Theriault","family":"Bell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Branstrator","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Roux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucille S.","family":"Hurley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,16]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(70)90387-6"},{"key":"e_1_2_1_3_1","first-page":"201","article-title":"Chromosomes and abortion","volume":"2","author":"Carr D. H.","year":"1971","journal-title":"Adv. Hum. Genet."},{"key":"e_1_2_1_4_1","first-page":"39","volume-title":"Trace Element Metabolism in Animals","author":"Chesters J. K.","year":"1973"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/26.3.292"},{"key":"e_1_2_1_6_1","first-page":"1585","article-title":"Droxyribonucleic acid synthesis, protein synthesia and teratogenesis in zinc\u2010deficiem rats","volume":"46","author":"Dreosti I. E.","year":"1972","journal-title":"S. Afr. Med. J."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420060109"},{"key":"e_1_2_1_8_1","first-page":"1","article-title":"Role of zinc in cell division of Euglend graicilis","volume":"17","author":"Falchuk K. H.","year":"1974","journal-title":"J. Cell. Sci."},{"key":"e_1_2_1_9_1","unstructured":"Hurley L. S.1971Magnesium deficiency during pregnancy and its effect on thc offspring. In: 1st Int. Symp. Magnesium Deficit Hum. Path. (Vittel France) Imprijnerie Amelot 27 Brionne France pp.481\u2013492."},{"key":"e_1_2_1_10_1","first-page":"516","article-title":"Congenital maltormations and fetal anemia resulting from magnesium deficiency in rats","volume":"30","author":"Hurley L. S.","year":"1971","journal-title":"Fed. Proc."},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420040211"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-366851-6.50007-7"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-123-31578"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420040306"},{"key":"e_1_2_1_15_1","first-page":"83","article-title":"Zinc deficiency: brain DNA, protein and lipids and liver ribosomes and RNA polymerase","volume":"19","author":"Sandstead H. H.","year":"1971","journal-title":"Clin. 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