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Main features were described permitting, on anatomic examination of the conceptus, diagnosis of genetic anomalies, and in some instances possibly assigning the type of chromosomal aberration: viz., in monosomy X, triploidies, tetraploidies, and some trisomies. Phenotypic expression at the cellular level was studied by morphometry of the placenta and by study of in\u2010vitro growth characteristics of cells lines initiated from aneuploid embryos. Study of growth rate characteristics may reveal the basis for the pathogenesis of developmental arrests.<\/jats:p>","DOI":"10.1002\/tera.1420140103","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T14:10:45Z","timestamp":1118499045000},"page":"3-19","source":"Crossref","is-referenced-by-count":96,"title":["Phenotypic expression of lethal chromosomal anomalies in human abortuses"],"prefix":"10.1002","volume":"14","author":[{"given":"Jo\u00eblle","family":"Boui\u00e9","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emile","family":"Philippe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Giroud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Bou\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,5,13]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"317","volume-title":"Physiology and Genetics of Reproduction","author":"Bou\u00e9 A.","year":"1975"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02616379"},{"key":"e_1_2_1_4_1","first-page":"1047","article-title":"Lign\u00e9es rellulaires hurnaines avec aberrations chromosomiques (trisomiques, monosorniques et tripl\u00f3ides), stabilit\u00e9 caryotypique, long\u00e9vit\u00e9","volume":"16","author":"Bou\u00e9 A.","year":"1968","journal-title":"Path. 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