{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T03:19:01Z","timestamp":1792207141212,"version":"4.4.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,5,19]],"date-time":"2005-05-19T00:00:00Z","timestamp":1116460800000},"content-version":"vor","delay-in-days":8873,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Teratology"],"published-print":{"date-parts":[[1981,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A detailed anatomopathologic study of the various developmental malformations encountered in a set of female thoracopagus twins is presented. Special emphasis has been devoted to the analysis and description of the complex cardiovascular abnormalities associated with the conjoined heart and liver of this set of twins. The heart was conjoined with two sets of great arteries. The great arteries of one twin were d\u2010malposed and originated from a single right ventricle; a normally placed aorta originated from a single left ventricle and the hypoplastic pulmonary trunk originated from a rudimentary outlet chamber of the other twin. One twin had two atria with the systemic veins returning to the right one and an anomalous pulmonary venous return terminating in the ductus venous of her liver. The other twin had a single right atrium plus an accessory atrial chamber to which both the pulmonary and the systemic veins returned. There were two umbilical arteries originating from the internal iliac arteries of one twin and two umbilical veins which fused into one as they entered into the ductus venosus of the other twin. The cardiovascular abnormalities of our case have been compared with those encountered in 25 well\u2010documented cases of thoracopagus twins previously reported in the literature. It was concluded that the majority of thoracopagus twins (approximately 75%) had conjoined heart with associated cardiovascular abnormalities making them unsuitable for surgical separation even at the cost of the life of one of them. In addition, an embryological interpretation concerning the possible origin of the cardiovascular abnormalities of our case is presented and discussed.<\/jats:p>","DOI":"10.1002\/tera.1420230113","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T14:36:47Z","timestamp":1118500607000},"page":"101-113","source":"Crossref","is-referenced-by-count":41,"title":["Cardiovascular abnormalities in thoracopagus twins"],"prefix":"10.1002","volume":"23","author":[{"given":"Miguel","family":"Marin\u2010Padilla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvin J.","family":"Chin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa M.","family":"Marin\u2010Padilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,5,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.1968.tb00678.x"},{"key":"e_1_2_1_3_1","first-page":"398","article-title":"The morphological theory of monocho\u2010rionic twins as illustrated by a series of supposed early twins embryos of the pig","volume":"33","author":"Corner G. W.","year":"1922","journal-title":"Bull. Johns Hopk. Hosp."},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1959.tb02054.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.56.3.491"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1090700302"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(48)90428-1"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.18.6.625"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(70)80003-0"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420060211"},{"key":"e_1_2_1_11_1","unstructured":"Guttmacher A. F. andB. L.Nichols(1967) Teratology of conjoined twins. In:Conjoined Twins. National Foundation\u2010March of Dimes. Birth Defects Original Article Series D. Bergsma ed. Vol. 3 pp.3\u20139."},{"key":"e_1_2_1_12_1","first-page":"19","article-title":"Assessment of the cardiovascular system in conjoined thoracopagus twins","volume":"132","author":"Izukawa T.","year":"1978","journal-title":"Am J. Dis. Child."},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1958.01280190037007"},{"key":"e_1_2_1_14_1","first-page":"157","article-title":"Figure of eight circulation in conjoined twins with shared heart","volume":"6","author":"Joffe H. S.","year":"1977","journal-title":"Eur. J. Cardiol."},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(57)90391-5"},{"key":"e_1_2_1_16_1","first-page":"235","article-title":"A thoracopagus with unusual cardiovascular anomalies","volume":"5","author":"Kranendonk G. H.","year":"1963","journal-title":"Acta Morphol. Neerl. Scand."},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196306202682504"},{"key":"e_1_2_1_18_1","series-title":"Birth Defects Original Article Series","first-page":"52","volume-title":"Conjoined Twins. National Foundation\u2010March of Dimes","author":"Leachmann R. D.","year":"1967"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.18004217517"},{"key":"e_1_2_1_20_1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1093\/ajcp\/13.4.215","article-title":"Conjoined fetuses (thoracopagus disymmetros) occurring in a set of mon\u2010ozygotic triplets. Report of a case","volume":"13","author":"Messinger R. F.","year":"1943","journal-title":"Am. J. Clin. Pathol."},{"key":"e_1_2_1_21_1","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/S0002-9378(16)40580-6","article-title":"Human thoracopagus monster (so\u2010called Siamese twins)","volume":"42","author":"Mortimer B.","year":"1941","journal-title":"Am. J. Obstet. Gynecol."},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1930.tb16123.x"},{"key":"e_1_2_1_23_1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1017\/S0001566000013842","article-title":"A case of conjoined twins","volume":"25","author":"Myrianthopoulos N. C.","year":"1976","journal-title":"Acta Genet. Med. Gemellol. (Rome)"},{"key":"e_1_2_1_24_1","series-title":"Birth Defects Original Article Series","first-page":"38","volume-title":"Conjoined Twins. National Foundation\u2010March of Dimes","author":"Nichols B. L.","year":"1967"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016347409157757"},{"key":"e_1_2_1_26_1","first-page":"207","volume-title":"Pathology of the Fetus and the Infant","author":"Potter E. L.","year":"1975"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1951.tb04024.x"},{"key":"e_1_2_1_28_1","first-page":"450","article-title":"Conjoined twins: Report of three cases","volume":"126","author":"Riker W.","year":"1964","journal-title":"Illinois Med. J."},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800510517"},{"key":"e_1_2_1_30_1","series-title":"Birth Defects Original Article Series","first-page":"28","volume-title":"Conjoined Twins. National Foundation\u2010March of Dimes","author":"Rudolph A. J.","year":"1967"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4831-9949-8.50012-2"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(34)90674-8"},{"key":"e_1_2_1_33_1","series-title":"Birth Defects Original Article Series","first-page":"97","volume-title":"Conjoined Twins. National Foundation\u2010March of Dimes","author":"Singer D. B.","year":"1967"},{"key":"e_1_2_1_34_1","series-title":"Birth Defects Original Article Series","first-page":"89","volume-title":"Conjoined Twins. National Foundation\u2010March of Dimes","author":"Singleton E. B.","year":"1967"},{"key":"e_1_2_1_35_1","first-page":"235","article-title":"Formation of single ovum twins","volume":"30","author":"Streeter G. L.","year":"1919","journal-title":"Bull. Johns Hopk. Hosp."},{"key":"e_1_2_1_36_1","first-page":"455","article-title":"Conjoined twins in triple pregnancy","volume":"122","author":"Tan K. L.","year":"1971","journal-title":"Am. J. Dis. Child."},{"key":"e_1_2_1_37_1","first-page":"248","article-title":"Thoracopagus twins. Report of a case","volume":"28","author":"Tandon R.","year":"1974","journal-title":"Arch. Pathol."},{"key":"e_1_2_1_38_1","series-title":"Birth Defects Original Article Series","first-page":"106","volume-title":"Conjoined Twins. National Foundation\u2010March of Dimes","author":"Vallbona C.","year":"1967"},{"key":"e_1_2_1_39_1","series-title":"Birth Defects Original Article Series","first-page":"18","volume-title":"Conjoined Twins. National Foundation\u2010March of Dimes","author":"Zimmerman A. A.","year":"1967"}],"container-title":["Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ftera.1420230113","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/tera.1420230113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T09:33:46Z","timestamp":1699781626000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/tera.1420230113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,2]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1981,2]]}},"alternative-id":["10.1002\/tera.1420230113"],"URL":"https:\/\/doi.org\/10.1002\/tera.1420230113","archive":["Portico"],"relation":{},"ISSN":["0040-3709","1096-9926"],"issn-type":[{"value":"0040-3709","type":"print"},{"value":"1096-9926","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,2]]}}}