{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T08:40:32Z","timestamp":1699778432541},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,5,19]],"date-time":"2005-05-19T00:00:00Z","timestamp":1116460800000},"content-version":"vor","delay-in-days":8631,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Teratology"],"published-print":{"date-parts":[[1981,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fetal malformations may introduce complications of maternal pregnancy. A polyhydramnios represents one such complication during pregnancy. We want to report five abnormal pregnancies which were marked by acute polyhydramnios and\/or premature labor due to an amniotic band syndrome associated with cerebral herniation in two cases, malignant oral teratoma in one case, bilateral cystic hygromas associated with generalized fetal hydrops in one case, and multiple internal malformations in one case, \u03b1<jats:sub>1<\/jats:sub>\u2010fetoprotein (AFP) values between the 25th and 34th week of gestation were elevated 3.5 to 44 times the normal median value. Since all fetuses showed severe malformations incompatible with life our observations indicate the necessity to determine AFP in cases of acute polyhydramnios independent of the week of gestation. Conversely, elevated AFP levels in amniotic fluid obtained during prenatal diagnosis in the 16th week of gestation may also suggest rare fetal malformations outlined above.<\/jats:p>","DOI":"10.1002\/tera.1420240203","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T13:10:06Z","timestamp":1118495406000},"page":"125-130","source":"Crossref","is-referenced-by-count":4,"title":["Congenital malformation syndromes and elevation of amniotic fluid \u03b1<sub>1<\/sub>\u2010fetoprotein"],"prefix":"10.1002","volume":"24","author":[{"given":"Uta","family":"Burck","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karsten R.","family":"Held","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans\u2010J.","family":"Kitschke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Carstensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1979.tb01745.x"},{"key":"e_1_2_1_3_1","first-page":"557","article-title":"\u03b11\u2010Fetoprotein\u2010diagno\u2010stische Bedeutung","volume":"16","author":"Gassner M.","year":"1974","journal-title":"Schweizerische Med. Wochenschr."},{"key":"e_1_2_1_4_1","first-page":"417","article-title":"Fetal Turner's syndrome","volume":"132","author":"Gellis S. S.","year":"1978","journal-title":"Am. J. Dis. Child."},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)90409-8"},{"key":"e_1_2_1_6_1","first-page":"279","article-title":"Amniotic fluid alpha\u2010fetoprotein elevation with fetal omphalocele and a possible mechanism for its occurrence","volume":"130","author":"King C. R.","year":"1978","journal-title":"Am. J. Obstet. Gynecol."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1975.tb00314.x"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016347609156785"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5918.524"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1975.tb25402.x"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/53.1.104"},{"key":"e_1_2_1_12_1","first-page":"697","article-title":"Origin of amniotic fluid alpha\u2010fetoprotein in normal and defective pregnancies","volume":"47","author":"Weiss R. R.","year":"1976","journal-title":"Obstet. Gynecol."},{"key":"e_1_2_1_13_1","first-page":"1005","article-title":"Pr\u00e4natale Diagnostik angeborener Fehlbildungen durch Alpha\u2010Fetoprotein\u2010Bestimmung","volume":"21","author":"Weitzel H. K.","year":"1979","journal-title":"Fortschr. Med."}],"container-title":["Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ftera.1420240203","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/tera.1420240203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T08:21:08Z","timestamp":1699777268000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/tera.1420240203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,10]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1981,10]]}},"alternative-id":["10.1002\/tera.1420240203"],"URL":"https:\/\/doi.org\/10.1002\/tera.1420240203","archive":["Portico"],"relation":{},"ISSN":["0040-3709","1096-9926"],"issn-type":[{"value":"0040-3709","type":"print"},{"value":"1096-9926","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,10]]}}}