{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T21:51:50Z","timestamp":1767649910566},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,5,19]],"date-time":"2005-05-19T00:00:00Z","timestamp":1116460800000},"content-version":"vor","delay-in-days":8570,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Teratology"],"published-print":{"date-parts":[[1981,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cassava is a tuberous root of a shrublike plant cultivated in tropical rain forests as a staple food in South Eastern Nigeria. Reports are on record showing correlation between cassava intake and occurrence of various types of neuropathies (Money, '59; Monekosso and Wilson, '66; Osuntokun et al., '68, '69). About 0.1\u20132 mg of cyanide\/100 gm is released from Cassava by action of hydrolase (Paula and Rangel, '46). It has been suspected by several local clinicians as a cause of congenital anomalies if consumed in excess during pregnancy. However, it remains a controversial problem and precise scientific data is lacking. This study was conducted on albino rats by giving them milled cassava powder as 50% and 80% of their diet during the first 15 days of pregnancy. Fetuses collected on day 20. from the group receiving cassava as 80% of the diet showed a low incidence of limb defects, open eye, microcephaly, and growth retardation in the rat. Interpretation of this data for the human should be made with caution.<\/jats:p>","DOI":"10.1002\/tera.1420240307","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T14:39:39Z","timestamp":1118500779000},"page":"289-291","source":"Crossref","is-referenced-by-count":21,"title":["The teratogenic effects of dietary cassava on the pregnant albino rat: A preliminary report"],"prefix":"10.1002","volume":"24","author":[{"given":"Jay Datta","family":"Singh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420100311"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420140110"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(66)91009-9"},{"key":"e_1_2_1_5_1","first-page":"58","article-title":"Clinical aspects of tropical ataxic neuropathies related to malnutrition","volume":"7","author":"Money G. L.","year":"1959","journal-title":"West Afr. Med. J."},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","unstructured":"Osuntokun R. O. H. McFerlane O.Durowoju andJ.Wilson(1968)Br. Med. J. 647.","DOI":"10.1136\/bmj.3.5619.647"},{"key":"e_1_2_1_7_1","first-page":"2161","volume":"39","author":"de Paula G.","year":"1946","journal-title":"Chem. Abstr."},{"key":"e_1_2_1_8_1","volume-title":"Thalidomide Embryopathy and Neuropathy","author":"Skre H.","year":"1962"},{"key":"e_1_2_1_9_1","first-page":"72A","article-title":"Thalidomide dysmelia: Proposed pathogenesis","volume":"21","author":"Theisen C. T.","year":"1980","journal-title":"Teratology"}],"container-title":["Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ftera.1420240307","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/tera.1420240307","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T08:28:24Z","timestamp":1699777704000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/tera.1420240307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,12]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1981,12]]}},"alternative-id":["10.1002\/tera.1420240307"],"URL":"https:\/\/doi.org\/10.1002\/tera.1420240307","archive":["Portico"],"relation":{},"ISSN":["0040-3709","1096-9926"],"issn-type":[{"value":"0040-3709","type":"print"},{"value":"1096-9926","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,12]]}}}