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No similar cases in anticonvulsantexposed pregnancies were found on literature review, despite the increased incidence of other anomalies following such exposure.<\/jats:p><jats:p>Goldenhar syndrome, especially related to rare central nervous system anomalies, is reviewed. Experimental production of hemifacial microsomia by a folic acid antagonist, triaxene, is mediated via hemorrhage in the fetus. Intraventricular hemorrhage was noted in this infant as were dilated lateral and third ventricles. The hemorrhagic diathesis and\/or the folic acid depletion of newborns following fetal anticonvulsant exposure may have been the underlying mechanism.<\/jats:p>","DOI":"10.1002\/tera.1420320103","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T14:54:42Z","timestamp":1118501682000},"page":"13-17","source":"Crossref","is-referenced-by-count":55,"title":["Goldenhar syndrome, anterior encephalocele, and aqueductal stenosis following fetal primidone exposure"],"prefix":"10.1002","volume":"32","author":[{"given":"Edward E.","family":"Gustavson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,5,24]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1975.tb03501.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00279415"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1982.tb09501.x"},{"key":"e_1_2_1_5_2","first-page":"548","volume-title":"The Pharmacological Basis of Therapeutics","author":"Gilman A. 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