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Offspring were examined for physical landmarks, neuromotor development, and behaviour using righting reflex, swimming, negative geotaxis, open field, rotarod, water maze, and nocturnal activity. This test battery included biochemical measurements. No reduction in parental weight and physical offspring development was observed. All these treatments produced long\u2010term changes in more than one test. Vitamin A palmitate (160,000 IU\/kg) was judged as the best positive control with this test battery for future investigation of the behavioural teratology of drugs.<\/jats:p>","DOI":"10.1002\/tera.1420370303","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T15:07:27Z","timestamp":1118502447000},"page":"185-199","source":"Crossref","is-referenced-by-count":22,"title":["Methodological proposal in behavioural teratogenicity testing: Assessment of propoxyphene, chlorpromazine, and vitamin A as positive controls"],"prefix":"10.1002","volume":"37","author":[{"given":"A. 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