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Concomitant with this observation were reductions in the amount of amniotic fluid, compared to controls, on day 18 of gestation and thereafter. When isoxsuprine HCl (2 mg\/kg, b.i.d.), a uterine muscle relaxant, was additionally injected ip to pregnant rats on days 17\u201319 of gestation, the incidence of wavy ribs was significantly (<jats:italic>P<\/jats:italic> \u2264 .05) less than that seen after treatment with furosemide alone. These observations indicate that the myometrial constriction plays a significant role in the induction of furosemide\u2010induced wavy ribs.<\/jats:p>","DOI":"10.1002\/tera.1420370406","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T15:07:32Z","timestamp":1118502452000},"page":"329-334","source":"Crossref","is-referenced-by-count":11,"title":["Role of myometrial constriction in the induction of wavy ribs in rat fetuses"],"prefix":"10.1002","volume":"37","author":[{"given":"Toshio","family":"Nakatsuka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,31]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(80)90134-9"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0773.1979.tb02374.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(76)90096-X"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(86)90278-4"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483X(78)90040-9"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-181-42276"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(85)90527-7"},{"key":"e_1_2_1_9_1","first-page":"94","article-title":"Osteolathyrogenic effects on the developing rat foetus","volume":"8","author":"Ferm V. 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