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The number of corpora lutea, total implants, and resorptions as well as the number of live and dead fetuses in the treated animals were not significantly different from the control group. Therefore, embryolethality of aluminum cannot be induced (as a measure of percent dead and resorbed fetuses). However, exposure of rats to aluminum nitrate resulted in decreased fetal body weight and increased the incidence and types of external, visceral, and skeletal malformations and variations in all the treated groups. Consequently, teratogenic effects of aluminum\u2010nitrate administration may result in rats given high oral doses that induce concomitant maternal toxicity.<\/jats:p>","DOI":"10.1002\/tera.1420380309","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T15:11:06Z","timestamp":1118502666000},"page":"253-257","source":"Crossref","is-referenced-by-count":52,"title":["Embryotoxic and teratogenic effects of aluminum nitrate in rats upon oral administration"],"prefix":"10.1002","volume":"38","author":[{"given":"Jose L.","family":"Paternain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose L.","family":"Domingo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan M.","family":"Llobet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacinto","family":"Corbella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197601222940402"},{"key":"e_1_2_1_3_1","first-page":"365","article-title":"Experimental studies on the effects of aluminum on pregnancy and fetal development","volume":"138","author":"Benett R. 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