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Combinations of diazepam and cocaine (20\/10 and 40\/20, respectively) were used. Significant reductions of fetal weight and length were found in the group treated with diazepam and cocaine (40\/20). The incidences of incomplete ossification of sternebrae and skull bones, as well as delayed ossification of the paws, were significantly increased in the combination groups. Hydronephrosis and cryptorchidism were observed in the cocaine\u2010treated groups, with the incidence of these malformations increasing significantly when diazepam was co\u2010administered.<\/jats:p>","DOI":"10.1002\/tera.1420430103","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T18:46:43Z","timestamp":1118515603000},"page":"11-17","source":"Crossref","is-referenced-by-count":27,"title":["Teratogenic effect of cocaine and diazepam in CF1 mice"],"prefix":"10.1002","volume":"43","author":[{"given":"Sherif Z.","family":"Mehanny","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed S.","family":"Abdel\u2010Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yehia Y.","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(75)92153-4"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","unstructured":"Abelson H. 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