{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T02:22:10Z","timestamp":1787970130189,"version":"build-2784847793"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,6,2]],"date-time":"2005-06-02T00:00:00Z","timestamp":1117670400000},"content-version":"vor","delay-in-days":4810,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Teratology"],"published-print":{"date-parts":[[1992,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To identify risk factors for gastroschisis other than drug use in pregnancy, an analysis of data collected in a case\u2010control surveillance program of birth defects (1976\u20101990) was conducted. Drug use is considered in Werler et al.,<jats:italic>Teratology, 45:<\/jats:italic>361\u2010367, 1992. Maternal demographic, reproductive, and medical factors, and first trimester environmental exposures, were compared between 76 gastroschisis cases and 2,581 malformed controls. A strong inverse association was found for maternal age: relative to women 30 years or older, relative risks for 25\u201029, 20\u201024, and &lt;20\u2010year\u2010old women were 1.7, 5.4, and 16, respectively. Multivariate relative risks (and 95% confidence intervals) for alcohol use were as follows: for 1\u20105 drinks per week, 1.6 (0.7\u20103.4); for \u2a7e6 drinks per week, 2.5 (0.9\u20106.8); for a maximum of 1\u20104 drinks at any one time, 0.8 (0.4\u20101.6); and for a maximum of \u2a7d5 drinks, 2.8 (1.2\u20106.5). With the effect of age taken into account, no associations were identified for cigarette smoking, consumption of caffeinated or decaffeinated coffee, unplanned pregnancy, 12 or less years of education, or a parity of two or more. Other medical and reproductive factors, including weight gain, vaginal bleeding, nausea or vomiting, influenza, \u201cother\u201d infection, and history of spontaneous abortion or elective abortion did not increase the risk.<\/jats:p>","DOI":"10.1002\/tera.1420450406","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T15:50:36Z","timestamp":1118505036000},"page":"353-360","source":"Crossref","is-referenced-by-count":82,"title":["Demographic, reproductive, medical, and environmental factors in relation to gastroschisis"],"prefix":"10.1002","volume":"45","author":[{"given":"Martha M.","family":"Werler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen A.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Shapiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,2]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"17","article-title":"Alcohol induced cardiac malformations in the rat","volume":"255","author":"Beauchemin R. R.","year":"1984","journal-title":"Anat. Anz."},{"key":"e_1_2_1_3_1","first-page":"1386","article-title":"Perinatal aspects of omphalocele and gastroschisis","volume":"131","author":"Colombani P. M.","year":"1977","journal-title":"Am. J. Dis. Child"},{"key":"e_1_2_1_4_1","first-page":"39","article-title":"Gastroschisis: A pilot study of its incidence and the possible influence of teratogenic factors","volume":"28","author":"Gierup J.","year":"1979","journal-title":"Z. Kinderchir."},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420420408"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.36.4.289"},{"key":"e_1_2_1_7_1","first-page":"294","article-title":"Gastroschisis: Abdominal wall disruption secondary to early gestational interruption of the omphalomesenteric artery","volume":"7","author":"Hoyme H. E.","year":"1983","journal-title":"Semin. Perinat."},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1542\/peds.85.5.743","article-title":"Prenatal cocaine exposure and fetal vascular disruption","volume":"85","author":"Hoyme H. E.","year":"1990","journal-title":"Pediatrics"},{"key":"e_1_2_1_9_1","first-page":"145","article-title":"Empiric recurrence risks and gastroschisis","volume":"15","author":"Jorgenson R. J.","year":"1979","journal-title":"Birth Defects"},{"key":"e_1_2_1_10_1","volume-title":"Epidemiologic research principles and quantitative methods","author":"Kleinbaum D. G.","year":"1982"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1981.tb07173.x"},{"key":"e_1_2_1_12_1","first-page":"211","article-title":"Teratogenic aspects of abdominal wall defects","volume":"38","author":"Lindham S.","year":"1983","journal-title":"Z. Kinderchir."},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420290308"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6890235"},{"key":"e_1_2_1_15_1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1001\/jama.1989.03420010066034","article-title":"Trends in cigarette smoking in the U.S","volume":"262","author":"Pierce J. P.","year":"1989","journal-title":"JAMA"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420350206"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1979.02130050058011"},{"key":"e_1_2_1_18_1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1542\/peds.74.1.94","article-title":"Gastroschisis in a case of dizygotic twins: The possible role of maternal alcohol consumption","volume":"74","author":"Sarda P.","year":"1984","journal-title":"Pediatrics"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00268a044"},{"key":"e_1_2_1_20_1","first-page":"59","volume-title":"Epidemiological Evaluation of Drugs","author":"Slone D.","year":"1977"},{"key":"e_1_2_1_21_1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3928\/00904481-19810601-06","article-title":"Fetal vascular disruption: mechanisms and some resulting birth defects","volume":"10","author":"Van Allen M. I.","year":"1981","journal-title":"Pediatric Ann."},{"key":"e_1_2_1_22_1","first-page":"131","volume-title":"Teratogen Update: Environmentally Induced Birth Defects Risks","author":"Werler M. M.","year":"1986"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420450407"},{"key":"e_1_2_1_24_1","volume-title":"Environment and Birth Defects","author":"Wilson J. G.","year":"1973"}],"container-title":["Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ftera.1420450406","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/tera.1420450406","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T16:03:49Z","timestamp":1735747429000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/tera.1420450406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,4]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1992,4]]}},"alternative-id":["10.1002\/tera.1420450406"],"URL":"https:\/\/doi.org\/10.1002\/tera.1420450406","archive":["Portico"],"relation":{},"ISSN":["0040-3709","1096-9926"],"issn-type":[{"value":"0040-3709","type":"print"},{"value":"1096-9926","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,4]]}}}