{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:04:40Z","timestamp":1791266680133,"version":"4.1.0"},"reference-count":33,"publisher":"Hindawi Limited","issue":"2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":2403,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Tissue Eng Regen Med"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1002\/term.137","type":"journal-article","created":{"date-parts":[[2008,12,8]],"date-time":"2008-12-08T08:46:14Z","timestamp":1228725974000},"page":"85-91","source":"Crossref","is-referenced-by-count":34,"title":["Reverse remodeling is associated with changes in extracellular matrix proteases and tissue inhibitors after mesenchymal stem cell (MSC) treatment of pressure overload hypertrophy"],"prefix":"10.1155","volume":"3","author":[{"given":"Ezequiel J.","family":"Molina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon","family":"Palma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipin","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Gaughan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Houser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahender","family":"Macha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"10.1002\/term.137-BIB1","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1161\/CIRCULATIONAHA.105.573865","article-title":"Matrix metalloproteinases\/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease","volume":"113","author":"Ahmed","year":"2006","journal-title":"Circulation"},{"key":"10.1002\/term.137-BIB2","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1161\/01.CIR.101.5.558","article-title":"\u03b2-Adrenergic receptor blockade in chronic heart failure","volume":"101","author":"Bristow","year":"2002","journal-title":"Circulation"},{"key":"10.1002\/term.137-BIB3","doi-asserted-by":"crossref","first-page":"1101.e1","DOI":"10.1016\/j.ahj.2006.02.029","article-title":"Tissue inhibitor of metalloproteinase-1 (TIMP-1) is an independent predictor of all-cause mortality, cardiac mortality, and myocardial infarction","volume":"151","author":"Cavusoglu","year":"2006","journal-title":"Am Heart J"},{"key":"10.1002\/term.137-BIB4","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0735-1097(99)00630-0","article-title":"Cardiac remodeling-concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. On behalf of an International Forum on Cardiac Remodeling","volume":"35","author":"Cohn","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1002\/term.137-BIB5","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.cardiores.2005.10.004","article-title":"Pathways of matrix metalloproteinase induction in heart failure: bioactive molecules and transcriptional regulation","volume":"69","author":"Deschamps","year":"2006","journal-title":"Cardiovasc Res"},{"key":"10.1002\/term.137-BIB6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.carpath.2004.12.002","article-title":"Cardiac remodeling and failure: from molecules to man (Part I)","volume":"14","author":"Fedak","year":"2005","journal-title":"Cardiovasc Pathol"},{"key":"10.1002\/term.137-BIB7","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.carpath.2005.01.005","article-title":"Cardiac remodeling and failure: From molecules to man (Part II)","volume":"14","author":"Fedak","year":"2005","journal-title":"Cardiovasc Pathol"},{"key":"10.1002\/term.137-BIB8","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.carpath.2005.03.004","article-title":"Cardiac remodeling and failure: from molecules to man (Part III)","volume":"14","author":"Fedak","year":"2005","journal-title":"Cardiovasc Pathol"},{"key":"10.1002\/term.137-BIB9","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1007\/s00109-004-0606-4","article-title":"Regulation of matrix metalloproteinases and their inhibitors in the left ventricular myocardium of patients with aortic stenosis","volume":"82","author":"Fielitz","year":"2004","journal-title":"J Mol Med"},{"key":"10.1002\/term.137-BIB10","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/S0003-4975(96)00389-X","article-title":"Cardiomyocyte transplantation improves heart function","volume":"62","author":"Li","year":"1996","journal-title":"Ann Thorac Surg"},{"key":"10.1002\/term.137-BIB11","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1006\/jmcc.1998.0882","article-title":"Smooth muscle cell transplantation into myocardial scar tissue improves heart function","volume":"31","author":"Li","year":"1999","journal-title":"J Mol Cell Cardiol"},{"key":"10.1002\/term.137-BIB12","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0022-5223(00)70218-2","article-title":"Autologous porcine heart cell transplantation improved heart function after a myocardial infarction","volume":"119","author":"Li","year":"2000","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1002\/term.137-BIB13","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/S0008-6363(00)00028-6","article-title":"MMP\/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACE- and MMP-inhibition","volume":"46","author":"Li","year":"2000","journal-title":"Cardiovasc Res"},{"key":"10.1002\/term.137-BIB14","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0962-8924(98)01362-2","article-title":"ECM signalling: orchestrating cell behaviour and misbehaviour","volume":"8","author":"Lukashev","year":"1998","journal-title":"Trends Cell Biol"},{"key":"10.1002\/term.137-BIB15","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1172\/JCI5298","article-title":"Cardiomyocytes can be generated from marrow stromal cells in vitro","volume":"103","author":"Makino","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1002\/term.137-BIB16","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.jtcvs.2007.10.003","article-title":"Improvement in hemodynamic performance, exercise capacity, inflammatory profile and left ventricular reverse remodeling after intra-coronary delivery of mesenchymal stem cells (MSC) in an experimental model of pressure overload hypertrophy","volume":"135","author":"Molina","year":"2008","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1002\/term.137-BIB17","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1161\/CIRCULATIONAHA.104.500447","article-title":"Transplantation of mesenchymal stem cells improves cardiac function in a rat model of dilated cardiomyopathy","volume":"112","author":"Nagaya","year":"2005","journal-title":"Circulation"},{"key":"10.1002\/term.137-BIB18","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0008-6363(00)00029-8","article-title":"Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat","volume":"46","author":"Peterson","year":"2000","journal-title":"Cardiovasc Res"},{"key":"10.1002\/term.137-BIB19","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/j.jacc.2004.07.023","article-title":"Matrix metalloproteinases and their tissue inhibitors in pressure-overloaded human myocardium during heart failure progression","volume":"44","author":"Polyakova","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1002\/term.137-BIB20","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1067\/mtc.2001.112937","article-title":"Cellular therapy reverses myocardial dysfunction","volume":"121","author":"Rajnoch","year":"2001","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1002\/term.137-BIB21","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0022-5223(03)00118-1","article-title":"Transcoronary implantation of bone marrow stromal cells ameliorates cardiac function after myocardial infarction","volume":"126","author":"Saito","year":"2003","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1002\/term.137-BIB22","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1038\/sj.gt.3301517","article-title":"Rat marrow stromal cells rapidly transduced with a self-inactivating retrovirus synthesize L-DOPA in vitro","volume":"16","author":"Schwarz","year":"2001","journal-title":"Gene Ther"},{"key":"10.1002\/term.137-BIB23","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1161\/01.CIR.0000151812.86142.45","article-title":"Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model","volume":"111","author":"Silva","year":"2005","journal-title":"Circulation"},{"key":"10.1002\/term.137-BIB24","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1161\/01.RES.86.12.1259","article-title":"Interleukin-1\u03b2 and tumor necrosis factor-\u03b1 decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro","volume":"86","author":"Siwik","year":"2000","journal-title":"Circ Res"},{"key":"10.1002\/term.137-BIB25","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1161\/01.RES.82.4.482","article-title":"Time-dependent changes in matrix metalloproteinase activity and expression during the progression of congestive heart failure: relation to ventricular and myocyte function","volume":"82","author":"Spinale","year":"1998","journal-title":"Circ Res"},{"key":"10.1002\/term.137-BIB26","doi-asserted-by":"crossref","first-page":"I213","DOI":"10.1161\/hc37t1.094929","article-title":"Intracoronary infusion of skeletal myoblasts improves cardiac function in doxorubicin-induced heart failure","volume":"104","author":"Suzuki","year":"2001","journal-title":"Circulation"},{"key":"10.1002\/term.137-BIB27","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1161\/01.CIR.97.17.1708","article-title":"Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy","volume":"97","author":"Thomas","year":"1998","journal-title":"Circulation"},{"key":"10.1002\/term.137-BIB28","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1067\/mtc.2002.120716","article-title":"Improved heart function with myogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplantation","volume":"123","author":"Tomita","year":"2002","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1002\/term.137-BIB29","doi-asserted-by":"crossref","first-page":"S465","DOI":"10.1054\/jcaf.2002.129289","article-title":"Relation between left ventricular remodeling and clinical outcomes in heart failure patients with left ventricular systolic dysfunction","volume":"8","author":"Udelson","year":"2002","journal-title":"J Card Fail"},{"key":"10.1002\/term.137-BIB30","doi-asserted-by":"crossref","first-page":"I54","DOI":"10.1161\/hc37t1.094777","article-title":"Regression of left ventricular hypertrophy after surgical therapy for aortic stenosis is associated with changes in extracellular matrix gene expression","volume":"104","author":"Walther","year":"2001","journal-title":"Circulation"},{"key":"10.1002\/term.137-BIB31","doi-asserted-by":"crossref","first-page":"H1393","DOI":"10.1152\/ajpheart.00871.2005","article-title":"Bioenergetic and functional consequences of stem cell-based VEGF delivery in pressure-overloaded swine hearts","volume":"290","author":"Wang","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1002\/term.137-BIB32","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1161\/CIRCULATIONAHA.105.600353","article-title":"Specific temporal profile of matrix metalloproteinase release occurs in patients after myocardial infarction: relation to left ventricular remodeling","volume":"114","author":"Webb","year":"2006","journal-title":"Circulation"},{"key":"10.1002\/term.137-BIB33","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.cardfail.2006.05.012","article-title":"Plasma matrix metalloproteinase-9 level is correlated with left ventricular volumes and ejection fraction in patients with heart failure","volume":"12","author":"Yan","year":"2006","journal-title":"J Card Fail"}],"container-title":["Journal of Tissue Engineering and Regenerative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fterm.137","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/term.137","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T13:21:57Z","timestamp":1671542517000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/term.137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"URL":"https:\/\/doi.org\/10.1002\/term.137","relation":{},"ISSN":["1932-6254","1932-7005"],"issn-type":[{"value":"1932-6254","type":"print"},{"value":"1932-7005","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,2]]}}}