{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T14:34:20Z","timestamp":1777646060604,"version":"3.51.4"},"reference-count":27,"publisher":"Hindawi Limited","issue":"12","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":944,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Tissue Eng Regen Med"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1002\/term.1691","type":"journal-article","created":{"date-parts":[[2013,1,30]],"date-time":"2013-01-30T09:43:07Z","timestamp":1359538987000},"page":"1386-1393","source":"Crossref","is-referenced-by-count":17,"title":["Recombinant human collagen III gel for transplantation of autologous skin cells in porcine full-thickness wounds"],"prefix":"10.1155","volume":"9","author":[{"given":"Kristo","family":"Nuutila","sequence":"first","affiliation":[{"name":"Institute of Biomedicine, Pharmacology; University of Helsinki; Finland"},{"name":"3rd Department of Surgery; Helsinki University Central Hospital; Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matti","family":"Peura","sequence":"additional","affiliation":[{"name":"Institute of Biomedicine, Pharmacology; University of Helsinki; Finland"},{"name":"3rd Department of Surgery; Helsinki University Central Hospital; Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sari","family":"Suomela","sequence":"additional","affiliation":[{"name":"Department of Dermatology; Helsinki University Central Hospital; Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mika","family":"Hukkanen","sequence":"additional","affiliation":[{"name":"Institute of Biomedicine, Anatomy; University of Helsinki; Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antti","family":"Siltanen","sequence":"additional","affiliation":[{"name":"Institute of Biomedicine, Pharmacology; University of Helsinki; Finland"},{"name":"3rd Department of Surgery; Helsinki University Central Hospital; Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ari","family":"Harjula","sequence":"additional","affiliation":[{"name":"Institute of Biomedicine, Pharmacology; University of Helsinki; Finland"},{"name":"3rd Department of Surgery; Helsinki University Central Hospital; Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyrki","family":"Vuola","sequence":"additional","affiliation":[{"name":"Helsinki Burn Centre, Department of Plastic Surgery; Helsinki University Central Hospital; Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esko","family":"Kankuri","sequence":"additional","affiliation":[{"name":"Institute of Biomedicine, Pharmacology; University of Helsinki; Finland"},{"name":"3rd Department of Surgery; Helsinki University Central Hospital; Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","published-online":{"date-parts":[[2013,1,30]]},"reference":[{"issue":"1","key":"10.1002\/term.1691-BIB0001|term1691-cit-0001","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1042\/bj1570263","article-title":"Presence of type III collagen in guinea pig dermal scar","volume":"157","author":"Barnes","year":"1976","journal-title":"Biochem J"},{"issue":"5","key":"10.1002\/term.1691-BIB0002|term1691-cit-0002","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1203\/PDR.0b013e31816c5bc3","article-title":"Collagen tissue engineering: development of novel biomaterials and applications","volume":"63","author":"Cen","year":"2008","journal-title":"Pediatr Res"},{"issue":"6","key":"10.1002\/term.1691-BIB0003|term1691-cit-0003","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1046\/j.1523-1747.1998.00200.x","article-title":"Organized skin structure is regenerated in vivo from collagen-GAG matrices seeded with autologous keratinocytes","volume":"110","author":"Compton","year":"1998","journal-title":"J Invest Dermatol"},{"key":"10.1002\/term.1691-BIB0004|term1691-cit-0004","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/eye.1988.28","article-title":"Wound closure: evidence of cooperation between fibroblasts and collagen matrix","volume":"2","author":"Ehrlich","year":"1988","journal-title":"Eye (Lond)"},{"key":"10.1002\/term.1691-BIB0005|term1691-cit-0005","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1111\/j.1752-8062.2008.00083.x","article-title":"Corneal regeneration following implantation of a biomimetic tissue-engineered substitute","volume":"2","author":"Fagerholm","year":"2009","journal-title":"Clin Transl Sci"},{"issue":"6","key":"10.1002\/term.1691-BIB0006|term1691-cit-0006","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1097\/00129334-200311000-00013","article-title":"Prevalence of lower-limb ulceration: a systematic review of prevalence studies","volume":"16","author":"Graham","year":"2003","journal-title":"Adv Skin Wound Care"},{"issue":"15","key":"10.1002\/term.1691-BIB0007|term1691-cit-0007","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1001\/jama.1989.03430150093032","article-title":"Burn wound closure with cultured autologous keratinocytes and fibroblasts attached to a collagen-glycosaminoglycan substrate","volume":"262","author":"Hansbrough","year":"1989","journal-title":"J Am Med Assoc"},{"issue":"3","key":"10.1002\/term.1691-BIB0008|term1691-cit-0008","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.biomaterials.2009.09.073","article-title":"Concentrated collagen hydrogels as dermal substitutes","volume":"31","author":"Helary","year":"2010","journal-title":"Biomaterials"},{"issue":"3","key":"10.1002\/term.1691-BIB0009|term1691-cit-0009","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1002\/jcb.23438","article-title":"Microarray-based identification of aminopeptidase N target genes in keratinocyte conditioned medium-stimulated dermal fibroblasts","volume":"113","author":"Lai","year":"2012","journal-title":"J Cell Biochem"},{"key":"10.1002\/term.1691-BIB0010|term1691-cit-0010","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1097\/PRS.0b013e3181eae781","article-title":"Scarless fetal wound healing: a basic science review","volume":"126","author":"Larson","year":"2010","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"10.1002\/term.1691-BIB0011|term1691-cit-0011","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/1523-1747.ep12616134","article-title":"Epidermal keratinocyte self-renewal is dependent upon dermal integrity","volume":"99","author":"Leary","year":"1992","journal-title":"J Invest Dermatol"},{"issue":"4","key":"10.1002\/term.1691-BIB0012|term1691-cit-0012","doi-asserted-by":"crossref","first-page":"493","DOI":"10.3181\/00379727-187-42694","article-title":"Type I and type III collagen content of healing wounds in fetal and adult rats","volume":"187","author":"Merkel","year":"1988","journal-title":"Proc Soc Exp Biol Med"},{"issue":"4","key":"10.1002\/term.1691-BIB0013|term1691-cit-0013","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1098\/rsif.2006.0179","article-title":"Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration","volume":"22","author":"Metcalfe","year":"2007","journal-title":"J R Soc Interface"},{"issue":"1","key":"10.1002\/term.1691-BIB0014|term1691-cit-0014","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0002-9610(99)80258-X","article-title":"Transplantation of keratinocytes in the treatment of wounds","volume":"170","author":"Myers","year":"1995","journal-title":"Am J Surg"},{"issue":"4","key":"10.1002\/term.1691-BIB0015|term1691-cit-0015","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.burns.2011.10.016","article-title":"Improved skin wound epithelialization by topical delivery of soluble factors from fibroblast aggregates","volume":"38","author":"Peura","year":"2011","journal-title":"Burns"},{"issue":"1","key":"10.1002\/term.1691-BIB0016|term1691-cit-0016","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1089\/teb.2007.0318","article-title":"Skin tissue engineering for tissue repair and regeneration","volume":"14","author":"Priya","year":"2008","journal-title":"Tissue Eng Part B Rev"},{"key":"10.1002\/term.1691-BIB0017|term1691-cit-0017","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.2741\/2277","article-title":"Wound reepithelialization: modulating keratinocyte migration in wound healing","volume":"12","author":"Raja","year":"2007","journal-title":"Front Biosci"},{"issue":"2","key":"10.1002\/term.1691-BIB0018|term1691-cit-0018","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1006\/jsre.1996.0210","article-title":"Current concepts in the development of cultured skin replacements","volume":"62","author":"Rennekampff","year":"1996","journal-title":"J Surg Res"},{"issue":"1","key":"10.1002\/term.1691-BIB0019|term1691-cit-0019","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.bbrc.2011.07.050","article-title":"3D collagen-dependent cell surface expression of MT1-MMP and MMP-2 activation regardless of integrin \u03b21 function and matrix stiffness","volume":"412","author":"Sakai","year":"2011","journal-title":"Biochem Biophys Res Commun"},{"issue":"2","key":"10.1002\/term.1691-BIB0020|term1691-cit-0020","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1524-475X.2009.00466.x","article-title":"Interactions between extracellular matrix and growth factors in wound healing","volume":"17","author":"Schultz","year":"2009","journal-title":"Wound Repair Regen"},{"issue":"6","key":"10.1002\/term.1691-BIB0021|term1691-cit-0021","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/j.1524-475X.2009.00543.x","article-title":"Human skin wounds: a major and snowballing threat to public health and the economy","volume":"17","author":"Sen","year":"2009","journal-title":"Wound Repair Regen"},{"issue":"47","key":"10.1002\/term.1691-BIB0022|term1691-cit-0022","doi-asserted-by":"crossref","first-page":"30022","DOI":"10.1016\/S0021-9258(18)43983-X","article-title":"Collagen-stimulated induction of keratinocyte collagenase is mediated via tyrosine kinase and protein kinase C activities","volume":"269","author":"Sudbeck","year":"1994","journal-title":"J Biol Chem"},{"issue":"7","key":"10.1002\/term.1691-BIB0023|term1691-cit-0023","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1097\/00007890-200204150-00004","article-title":"Cultured autologous fibroblasts augment epidermal repair","volume":"73","author":"Svensj\u00f6","year":"2002","journal-title":"Transplantation"},{"issue":"3","key":"10.1002\/term.1691-BIB0024|term1691-cit-0024","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.burns.2009.07.012","article-title":"Biological background of dermal substitutes","volume":"36","author":"Veen","year":"2010","journal-title":"Burns"},{"issue":"1","key":"10.1002\/term.1691-BIB0025|term1691-cit-0025","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jss.2008.10.001","article-title":"Cell suspensions of autologous keratinocytes or autologous fibroblasts accelerate the healing of full thickness skin wounds in a diabetic porcine wound healing model","volume":"157","author":"Velander","year":"2009","journal-title":"J Surg Res"},{"issue":"2","key":"10.1002\/term.1691-BIB0026|term1691-cit-0026","doi-asserted-by":"crossref","first-page":"103","DOI":"10.2165\/00063030-200418020-00004","article-title":"The application of recombinant human collagen in tissue engineering","volume":"18","author":"Yang","year":"2004","journal-title":"BioDrugs"},{"issue":"1","key":"10.1002\/term.1691-BIB0027|term1691-cit-0027","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1078\/0171-9335-00134","article-title":"Collagen-induced proMMP-2 activation by MT1-MMP in human dermal fibroblasts and the possible role of \u03b12\u03b21 integrins","volume":"80","author":"Zigrino","year":"2001","journal-title":"Eur J Cell Biol"}],"container-title":["Journal of Tissue Engineering and Regenerative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fterm.1691","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/term.1691\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T13:25:23Z","timestamp":1671542723000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/term.1691"}},"subtitle":["rhCol-III gel for wound healing"],"short-title":[],"issued":{"date-parts":[[2013,1,30]]},"references-count":27,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"URL":"https:\/\/doi.org\/10.1002\/term.1691","archive":["Portico"],"relation":{},"ISSN":["1932-6254"],"issn-type":[{"value":"1932-6254","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1,30]]}}}