{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T15:54:51Z","timestamp":1758815691599,"version":"3.37.3"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T00:00:00Z","timestamp":1493251200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T00:00:00Z","timestamp":1493251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Short Bowel Survivor and Friends Charity"},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/K026739\/1"],"award-info":[{"award-number":["MR\/K026739\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000291","name":"Kidney Research UK","doi-asserted-by":"publisher","award":["Postdoctoral Research Fellowship"],"award-info":[{"award-number":["Postdoctoral Research Fellowship"]}],"id":[{"id":"10.13039\/501100000291","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Tissue Eng Regen Med"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1002\/term.2409","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T16:36:27Z","timestamp":1484325387000},"page":"252-264","source":"Crossref","is-referenced-by-count":5,"title":["Exogenous transforming growth factor-<b>\u03b2<\/b>1 enhances smooth muscle differentiation in embryonic mouse jejunal explants"],"prefix":"10.1155","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3878-1415","authenticated-orcid":false,"given":"Riccardo","family":"Coletta","sequence":"first","affiliation":[{"name":"Institute of Human Development, Faculty of Medical and Human Sciences; University of Manchester; UK"},{"name":"Paediatric Autologous Bowel Reconstruction and Rehabilitation Unit, Department of Paediatric Surgery, Royal Manchester Children's Hospital; Central Manchester Foundation Trust; Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil A.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Institute of Human Development, Faculty of Medical and Human Sciences; University of Manchester; UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Randles","sequence":"additional","affiliation":[{"name":"Institute of Human Development, Faculty of Medical and Human Sciences; University of Manchester; UK"},{"name":"Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences; University of Manchester; Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonino","family":"Morabito","sequence":"additional","affiliation":[{"name":"Paediatric Autologous Bowel Reconstruction and Rehabilitation Unit, Department of Paediatric Surgery, Royal Manchester Children's Hospital; Central Manchester Foundation Trust; Manchester UK"},{"name":"Institute of Inflammation and Repair, Faculty of Medical and Human Sciences; University of Manchester Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5541-1358","authenticated-orcid":false,"given":"Adrian S.","family":"Woolf","sequence":"additional","affiliation":[{"name":"Institute of Human Development, Faculty of Medical and Human Sciences; University of Manchester; UK"},{"name":"Department of Paediatric Nephrology, Royal Manchester Children's Hospital; Central Manchester Foundation Trust; Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,27]]},"reference":[{"key":"10.1002\/term.2409-BIB0001|term2409-cit-0002","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1038\/nrd3810","article-title":"Targeting the TGF\u03b2 signalling pathway in disease","volume":"11","author":"Akhurst","year":"2012","journal-title":"Nat Rev Drug Discov"},{"key":"10.1002\/term.2409-BIB0002|term2409-cit-0003","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/S0960-9822(06)00340-X","article-title":"Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas","volume":"7","author":"Apelqvist","year":"1997","journal-title":"Curr Biol"},{"key":"10.1002\/term.2409-BIB0003|term2409-cit-0004","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1093\/bioinformatics\/17.6.509","article-title":"A Bayesian framework for the analysis of microarray expression data: regularized t-test and statistical inferences of gene changes","volume":"17","author":"Baldi","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1002\/term.2409-BIB0004|term2409-cit-0005","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0016-5085(93)90011-Z","article-title":"Localization of transforming growth factor \u03b2 isoforms in the normal murine small intestine and colon","volume":"105","author":"Barnard","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1002\/term.2409-BIB0005|term2409-cit-0006","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.ydbio.2008.11.020","article-title":"Wnt5a is essential for intestinal elongation in mice","volume":"326","author":"Cervantes","year":"2009","journal-title":"Dev Biol"},{"key":"10.1002\/term.2409-BIB0006|term2409-cit-0007","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1046\/j.1523-1755.2001.0590051641.x","article-title":"In vitro studies on the roles of transforming growth factor-\u03b21 in rat metanephric development","volume":"59","author":"Clark","year":"2001","journal-title":"Kidney Int"},{"key":"10.1002\/term.2409-BIB0007|term2409-cit-0008","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1053\/j.sempedsurg.2014.09.010","article-title":"Short bowel syndrome in children: surgical and medical perspectives","volume":"23","author":"Coletta","year":"2014","journal-title":"Semin Pediatr Surg"},{"key":"10.1002\/term.2409-BIB0008|term2409-cit-0009","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1002\/term.2073","article-title":"Bridging the gap: functional healing of embryonic small intestine ex vivo","volume":"10","author":"Coletta","year":"2016","journal-title":"J Tissue Eng Regen Med"},{"key":"10.1002\/term.2409-BIB0009|term2409-cit-0010","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1242\/dev.121.6.1845","article-title":"Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice","volume":"121","author":"Dickson","year":"1995","journal-title":"Development"},{"key":"10.1002\/term.2409-BIB0010|term2409-cit-0011","doi-asserted-by":"crossref","first-page":"2959","DOI":"10.1242\/dev.020453","article-title":"Fgf9 signaling regulates small intestinal elongation and mesenchymal development","volume":"135","author":"Geske","year":"2008","journal-title":"Development"},{"key":"10.1002\/term.2409-BIB0011|term2409-cit-0012","doi-asserted-by":"crossref","first-page":"4853","DOI":"10.1096\/fj.12-218578","article-title":"Human amniotic fluid stem cell differentiation along smooth muscle lineage","volume":"27","author":"Ghionzoli","year":"2013","journal-title":"FASEB J"},{"key":"10.1002\/term.2409-BIB0012|term2409-cit-0013","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1016\/j.jpedsurg.2013.08.006","article-title":"Royal Australasia of Surgeons Guest Lecture. Necrotizing enterocolitis: prevention, treatment, and outcome","volume":"48","author":"Hall","year":"2013","journal-title":"J Pediatr Surg"},{"key":"10.1002\/term.2409-BIB0013|term2409-cit-0014","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/j.1440-169X.1994.00567.x","article-title":"Transforming growth factor-\u03b21 inhibits growth and branching morphogenesis in embryonic mouse submandibular and sublingual glands in vitro","volume":"36","author":"Hardman","year":"1994","journal-title":"Develop Growth Differ"},{"key":"10.1002\/term.2409-BIB0014|term2409-cit-0015","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang da","year":"2009a","journal-title":"Nat Protoc"},{"key":"10.1002\/term.2409-BIB0015|term2409-cit-0016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/nar\/gkn923","article-title":"Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists","volume":"37","author":"Huang da","year":"2009b","journal-title":"Nucleic Acids Res"},{"key":"10.1002\/term.2409-BIB0016|term2409-cit-0017","doi-asserted-by":"crossref","first-page":"C499","DOI":"10.1152\/ajpcell.00480.2010","article-title":"Smad2 and PEA3 cooperatively regulate transcription of response gene to complement 32 in TGF-\u03b2-induced smooth muscle cell differentiation of neural crest cells","volume":"301","author":"Huang","year":"2011","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1002\/term.2409-BIB0017|term2409-cit-0018","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1432-0436.1990.tb00434.x","article-title":"Smooth muscle actin expression during rat gut development and induction in fetal skin fibroblastic cells associated with intestinal embryonic epithelium","volume":"43","author":"Kedinger","year":"1990","journal-title":"Differentiation"},{"key":"10.1002\/term.2409-BIB0018|term2409-cit-0019","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1073\/pnas.90.2.770","article-title":"Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death","volume":"90","author":"Kulkarni","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1002\/term.2409-BIB0019|term2409-cit-0020","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1365-2982.2007.01055.x","article-title":"Platelet-derived growth factor signals play critical roles in differentiation of longitudinal smooth muscle cells in mouse embryonic gut","volume":"20","author":"Kurahashi","year":"2008","journal-title":"Neurogastroenterol Motil"},{"key":"10.1002\/term.2409-BIB0020|term2409-cit-0021","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1126\/science.8009224","article-title":"Maternal rescue of transforming growth factor-beta 1 null mice","volume":"264","author":"Letterio","year":"1994","journal-title":"Science"},{"key":"10.1002\/term.2409-BIB0021|term2409-cit-0022","doi-asserted-by":"crossref","first-page":"3422","DOI":"10.4049\/jimmunol.1401779","article-title":"Noncanonical STAT3 activation regulates excess TGF-\u03b21 and collagen I expression in muscle of stricturing Crohn's disease","volume":"194","author":"Li","year":"2015","journal-title":"J Immunol"},{"key":"10.1002\/term.2409-BIB0022|term2409-cit-0023","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1387\/ijdb.082610bl","article-title":"Signalling molecules involved in mouse bladder smooth muscle cellular differentiation","volume":"54","author":"Liu","year":"2010","journal-title":"Int J Dev Biol"},{"key":"10.1002\/term.2409-BIB0023|term2409-cit-0024","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1053\/j.sempedsurg.2014.09.014","article-title":"Organ bioengineering for the newborn","volume":"23","author":"Maghsoudlou","year":"2014","journal-title":"Semin Pediatr Surg"},{"key":"10.1002\/term.2409-BIB0024|term2409-cit-0025","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/S0022-3468(99)90104-5","article-title":"Abnormalities of enteric neurons, intestinal pacemaker cells, and smooth muscle in human intestinal atresia","volume":"34","author":"Masumoto","year":"1999","journal-title":"J Pediatr Surg"},{"key":"10.1002\/term.2409-BIB0025|term2409-cit-0026","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1095\/biolreprod.103.026179","article-title":"Fetal and maternal transforming growth factor-\u03b21 may combine to maintain pregnancy in mice","volume":"70","author":"McLennan","year":"2004","journal-title":"Biol Reprod"},{"key":"10.1002\/term.2409-BIB0026|term2409-cit-0027","doi-asserted-by":"crossref","first-page":"e13984","DOI":"10.1371\/journal.pone.0013984","article-title":"Enrichment map: a network-based method for gene-set enrichment visualization and interpretation","volume":"5","author":"Merico","year":"2010","journal-title":"PLoS One"},{"key":"10.1002\/term.2409-BIB0027|term2409-cit-0028","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1126\/science.1223821","article-title":"Wnt5a potentiates TGF-\u03b2 signaling to promote colonic crypt regeneration after tissue injury","volume":"338","author":"Miyoshi","year":"2012","journal-title":"Science"},{"issue":"Suppl I","key":"10.1002\/term.2409-BIB0028|term2409-cit-0029","first-page":"I371","article-title":"Overexpression of transforming growth factor-\u03b2 is associated with increased hyaluronan content and impairment of repair in Marfan syndrome aortic aneurysm","volume":"114","author":"Nataatmadja","year":"2006","journal-title":"Circulation"},{"key":"10.1002\/term.2409-BIB0029|term2409-cit-0030","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1006\/dbio.1996.0259","article-title":"TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis","volume":"179","author":"Oshima","year":"1996","journal-title":"Dev Biol"},{"key":"10.1002\/term.2409-BIB0030|term2409-cit-0031","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1203\/00006450-199810000-00010","article-title":"Transforming growth factor-\u03b2 levels in maternal milk and expression in postnatal rat duodenum and ileum","volume":"44","author":"Penttila","year":"1998","journal-title":"Pediatr Res"},{"key":"10.1002\/term.2409-BIB0031|term2409-cit-0032","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1038\/35076576","article-title":"Computational analysis of microarray data","volume":"2","author":"Quackenbush","year":"2001","journal-title":"Nat Rev Genet"},{"key":"10.1002\/term.2409-BIB0032|term2409-cit-0033","doi-asserted-by":"crossref","first-page":"3163","DOI":"10.1242\/dev.121.10.3163","article-title":"Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut","volume":"121","author":"Roberts","year":"1995","journal-title":"Development"},{"key":"10.1002\/term.2409-BIB0033|term2409-cit-0034","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1053\/j.gastro.2015.07.004","article-title":"SOX9 maintains reserve stem cells and preserves radioresistance in mouse small intestine","volume":"149","author":"Roche","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1002\/term.2409-BIB0034|term2409-cit-0035","first-page":"F996","article-title":"Metanephric transforming growth factor-\u03b21 regulates nephrogenesis in vitro","volume":"264","author":"Rogers","year":"1993","journal-title":"Am J Phys"},{"key":"10.1002\/term.2409-BIB0035|term2409-cit-0036","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/MOG.0b013e3280145082","article-title":"Intestinal morphogenesis","volume":"23","author":"Rubin","year":"2007","journal-title":"Curr Opin Gastroenterol"},{"key":"10.1002\/term.2409-BIB0036|term2409-cit-0037","first-page":"237","volume-title":"Langman's Medical Embryology","author":"Sadler","year":"1990"},{"key":"10.1002\/term.2409-BIB0037|term2409-cit-0038","doi-asserted-by":"crossref","first-page":"374","DOI":"10.2144\/03342mt01","article-title":"TM4: a free, open-source system for microarray data management and analysis","volume":"34","author":"Saeed","year":"2003","journal-title":"Biotechniques"},{"key":"10.1002\/term.2409-BIB0038|term2409-cit-0039","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res"},{"key":"10.1002\/term.2409-BIB0039|term2409-cit-0040","doi-asserted-by":"crossref","first-page":"9440","DOI":"10.1073\/pnas.1530509100","article-title":"Statistical significance for genomewide studies","volume":"100","author":"Storey","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1002\/term.2409-BIB0040|term2409-cit-0041","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.diff.2008.10.003","article-title":"The expression and crucial roles of BMP signaling in development of smooth muscle progenitor cells in the mouse embryonic gut","volume":"77","author":"Torihashi","year":"2009","journal-title":"Differentiation"},{"key":"10.1002\/term.2409-BIB0041|term2409-cit-0042","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1053\/j.sempedsurg.2009.11.001","article-title":"Short bowel syndrome: epidemiology and etiology","volume":"19","author":"Wales","year":"2010","journal-title":"Semin Pediatr Surg"},{"key":"10.1002\/term.2409-BIB0042|term2409-cit-0043","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1242\/dev.097386","article-title":"How to make an intestine","volume":"141","author":"Wells","year":"2014","journal-title":"Development"},{"key":"10.1002\/term.2409-BIB0043|term2409-cit-0044","doi-asserted-by":"crossref","first-page":"5317","DOI":"10.1242\/dev.02141","article-title":"The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature","volume":"132","author":"Wilm","year":"2005","journal-title":"Development"},{"key":"10.1002\/term.2409-BIB0044|term2409-cit-0045","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1007\/s10620-012-2515-7","article-title":"Functional roles of TGF-\u03b21 in intestinal epithelial cells through Smad-dependent and non-Smad pathways","volume":"58","author":"Yamada","year":"2013","journal-title":"Dig Dis Sci"},{"key":"10.1002\/term.2409-BIB0045|term2409-cit-0046","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1016\/S0002-9440(10)64801-8","article-title":"Potential biological role of transforming growth factor-\uf0621 in human congenital kidney malformations","volume":"157","author":"Yang","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1002\/term.2409-BIB0046|term2409-cit-0047","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/pr.2016.150","article-title":"Milk growth factors and expression of small intestinal growth factor receptors during the perinatal period in mice","volume":"80","author":"Zhang","year":"2016","journal-title":"Pediatr Res"}],"container-title":["Journal of Tissue Engineering and Regenerative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fterm.2409","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/term.2409","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T13:24:47Z","timestamp":1671542687000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/term.2409"}},"subtitle":["TGF<b>\u03b2<\/b>and intestinal development"],"short-title":[],"issued":{"date-parts":[[2017,4,27]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"URL":"https:\/\/doi.org\/10.1002\/term.2409","archive":["Portico"],"relation":{},"ISSN":["1932-6254"],"issn-type":[{"type":"print","value":"1932-6254"}],"subject":[],"published":{"date-parts":[[2017,4,27]]}}}