{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:36:52Z","timestamp":1759412212688,"version":"3.37.3"},"reference-count":41,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T00:00:00Z","timestamp":1536710400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T00:00:00Z","timestamp":1536710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Tissue Eng Regen Med"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1002\/term.2731","type":"journal-article","created":{"date-parts":[[2018,7,25]],"date-time":"2018-07-25T13:48:05Z","timestamp":1532526485000},"page":"2125-2137","source":"Crossref","is-referenced-by-count":8,"title":["Cell-enrichment with olfactory ensheathing cells has limited local extra beneficial effects on nerve regeneration supported by the nerve guide Perimaix"],"prefix":"10.1155","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5738-7582","authenticated-orcid":false,"given":"Arne Hendrik","family":"Boecker","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, Reconstructive and Hand Surgery, Burn Center; University Hospital RWTH Aachen; Aachen Germany"},{"name":"Department of Hand-Plastic and Reconstructive Surgery, Burn Trauma Center, BG Trauma Center Ludwigshafen; University of Heidelberg; Ludwigshafen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Bozkurt","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Reconstructive and Hand Surgery, Burn Center; University Hospital RWTH Aachen; Aachen Germany"},{"name":"Department of Plastic, Hand, Reconstructive and Aesthetic Surgery, Helios Klinikum Wuppertal; University Witten\/Herdecke; Wuppertal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bong Sung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Reconstructive and Hand Surgery, Burn Center; University Hospital RWTH Aachen; Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haktan","family":"Altinova","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery; University Hospital RWTH Aachen; Aachen Germany"},{"name":"Institute of Neuropathology; University Hospital RWTH Aachen; Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Tank","sequence":"additional","affiliation":[{"name":"Department of General, Visceral and Thoracic Surgery; Private Medical University; Nuremberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"Deumens","sequence":"additional","affiliation":[{"name":"Neuropharmacology; Universit\u00e9 Catholique de Louvain; Brussels Belgium"},{"name":"Institute of Neuropathology; University Hospital RWTH Aachen; Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rene","family":"Tolba","sequence":"additional","affiliation":[{"name":"Institute for Laboratory Animal Research; University Hospital RWTH Aachen; Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Weis","sequence":"additional","affiliation":[{"name":"Institute of Neuropathology; University Hospital RWTH Aachen; Aachen Germany"},{"name":"Translational Brain Medicine (JARA Brain); Juelich-Aachen Research Alliance; Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary Anthony","family":"Brook","sequence":"additional","affiliation":[{"name":"Institute of Neuropathology; University Hospital RWTH Aachen; Aachen Germany"},{"name":"Translational Brain Medicine (JARA Brain); Juelich-Aachen Research Alliance; Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Pallua","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Reconstructive and Hand Surgery, Burn Center; University Hospital RWTH Aachen; Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabien Geraldine Antonia","family":"van Neerven","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Reconstructive and Hand Surgery, Burn Center; University Hospital RWTH Aachen; Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,12]]},"reference":[{"issue":"4","key":"10.1002\/term.2731-BIB0001|term2731-cit-0002","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/glia.10044","article-title":"Identification of growth factors that promote long-term proliferation of olfactory ensheathing cells and modulate their antigenic phenotype","volume":"37","author":"Alexander","year":"2002","journal-title":"Glia"},{"key":"10.1002\/term.2731-BIB0002|term2731-cit-0003","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s13770-016-9115-0","article-title":"Functional recovery not correlated with axon regeneration through olfactory ensheathing cell-seeded scaffolds in a model of acute spinal cord injury","volume":"13","author":"Altinova","year":"2016","journal-title":"Journal of Tissue Engineering and Regenerative Medicine"},{"key":"10.1002\/term.2731-BIB0003|term2731-cit-0004","doi-asserted-by":"crossref","first-page":"183","DOI":"10.4193\/Rhin15.365","article-title":"Safety of human olfactory mucosal biopsy for the purpose of olfactory ensheathing cell harvest and nerve repair: A prospective controlled study in patients undergoing endoscopic sinus surgery","volume":"54","author":"Andrews","year":"2016","journal-title":"Rhinology"},{"unstructured":"ASPN - Impact of Age on Outcomes in Peripheral Nerve Repair with Processed Nerve Allograft 2015 http:\/\/peripheralnerve.org\/meeting\/abstracts\/2015\/13.cgi","key":"10.1002\/term.2731-BIB0004|term2731-cit-0005"},{"issue":"7","key":"10.1002\/term.2731-BIB0005|term2731-cit-0006","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1055\/s-2001-17755","article-title":"Standardizing nerve crushes with a non-serrated clamp","volume":"17","author":"Beer","year":"2001","journal-title":"Journal of Reconstructive Microsurgery"},{"issue":"19","key":"10.1002\/term.2731-BIB0006|term2731-cit-0007","first-page":"3515","article-title":"Peripheral nerve regeneration: An opinion on channels, scaffolds and anisotropy","volume":"27","author":"Bellamkonda","year":"2006","journal-title":"Biomaterials"},{"key":"10.1002\/term.2731-BIB0007|term2731-cit-0008","article-title":"Pre-differentiation of mesenchymal stromal cells in combination with a microstructured nerve guide supports peripheral nerve regeneration in the rat sciatic nerve model","author":"Boecker","year":"2015","journal-title":"The European Journal of Neuroscience"},{"key":"10.1002\/term.2731-BIB0008|term2731-cit-0009","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.biomaterials.2015.10.009","article-title":"Efficient bridging of 20 mm rat sciatic nerve lesions with a longitudinally micro-structured collagen scaffold","volume":"75","author":"Bozkurt","year":"2015","journal-title":"Biomaterials"},{"issue":"12","key":"10.1002\/term.2731-BIB0009|term2731-cit-0010","doi-asserted-by":"crossref","first-page":"2971","DOI":"10.1089\/ten.2007.0116","article-title":"In vitro assessment of axonal growth using dorsal root ganglia explants in a novel three-dimensional collagen matrix","volume":"13","author":"Bozkurt","year":"2007","journal-title":"Tissue Engineering"},{"issue":"10","key":"10.1002\/term.2731-BIB0010|term2731-cit-0011","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1179\/1743132811Y.0000000029","article-title":"Epineurial sheath tube (EST) technique: An experimental peripheral nerve repair model","volume":"33","author":"Bozkurt","year":"2011","journal-title":"Neurological Research"},{"issue":"5","key":"10.1002\/term.2731-BIB0011|term2731-cit-0012","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/j.biomaterials.2011.10.069","article-title":"The role of microstructured and interconnected pore channels in a collagen-based nerve guide on axonal regeneration in peripheral nerves","volume":"33","author":"Bozkurt","year":"2012","journal-title":"Biomaterials"},{"issue":"1","key":"10.1002\/term.2731-BIB0012|term2731-cit-0013","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.bbr.2010.12.018","article-title":"Aspects of static and dynamic motor function in peripheral nerve regeneration: SSI and CatWalk gait analysis","volume":"219","author":"Bozkurt","year":"2011","journal-title":"Behavioural Brain Research"},{"issue":"1","key":"10.1002\/term.2731-BIB0013|term2731-cit-0014","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jneumeth.2008.01.006","article-title":"Evaluation of functional nerve recovery with Visual-SSI-A novel computerized approach for the assessment of the static sciatic index (SSI)","volume":"170","author":"Bozkurt","year":"2008","journal-title":"Journal of Neuroscience Methods"},{"key":"10.1002\/term.2731-BIB0014|term2731-cit-0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/121452","article-title":"The proximal medial sural nerve biopsy model: A standardised and reproducible baseline clinical model for the translational evaluation of bioengineered nerve guides","volume":"2014","author":"Bozkurt","year":"2014","journal-title":"BioMed Research International"},{"issue":"1","key":"10.1002\/term.2731-BIB0015|term2731-cit-0016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/micr.20975","article-title":"Processed nerve allografts for peripheral nerve reconstruction: A multicenter study of utilization and outcomes in sensory, mixed, and motor nerve reconstructions","volume":"32","author":"Brooks","year":"2011","journal-title":"Microsurgery"},{"issue":"5","key":"10.1002\/term.2731-BIB0016|term2731-cit-0017","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1002\/jor.1100100508","article-title":"The functional recovery of peripheral nerves following defined acute crush injuries","volume":"10","author":"Chen","year":"1992","journal-title":"Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society"},{"key":"10.1002\/term.2731-BIB0017|term2731-cit-0018","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.pneurobio.2015.06.001","article-title":"Trends in the design of nerve guidance channels in peripheral nerve tissue engineering","volume":"131","author":"Chiono","year":"2015","journal-title":"Progress in Neurobiology"},{"issue":"3","key":"10.1002\/term.2731-BIB0018|term2731-cit-0019","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.pneurobio.2010.10.002","article-title":"Repairing injured peripheral nerves: Bridging the gap","volume":"92","author":"Deumens","year":"2010","journal-title":"Progress in Neurobiology"},{"issue":"1-2","key":"10.1002\/term.2731-BIB0019|term2731-cit-0020","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.neulet.2005.11.063","article-title":"Neurite outgrowth promoting effects of enriched and mixed OEC\/ONF cultures","volume":"397","author":"Deumens","year":"2006","journal-title":"Neuroscience Letters"},{"issue":"9","key":"10.1002\/term.2731-BIB0020|term2731-cit-0021","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1016\/j.bjps.2009.09.012","article-title":"Adipose-derived stem cells enhance peripheral nerve regeneration","volume":"63","author":"Summa","year":"2010","journal-title":"Journal of Plastic, Reconstructive & Aesthetic Surgery"},{"issue":"7","key":"10.1002\/term.2731-BIB0021|term2731-cit-0022","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/micr.10056","article-title":"Reconstruction of peripheral nerves using acellular nerve grafts with implanted cultured Schwann cells","volume":"22","author":"Frerichs","year":"2002","journal-title":"Microsurgery"},{"issue":"30","key":"10.1002\/term.2731-BIB0022|term2731-cit-0023","doi-asserted-by":"crossref","first-page":"7705","DOI":"10.1016\/j.biomaterials.2010.06.060","article-title":"Cell-cell interactions of human neural progenitor-derived astrocytes within a microstructured 3D-scaffold","volume":"31","author":"F\u00fchrmann","year":"2010","journal-title":"Biomaterials"},{"key":"10.1002\/term.2731-BIB0023|term2731-cit-0024","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.brainres.2016.09.021","article-title":"Olfactory ensheathing glia cell therapy and tubular conduit enhance nerve regeneration after mouse sciatic nerve transection","volume":"1650","author":"Goulart","year":"2016","journal-title":"Brain Research"},{"key":"10.1002\/term.2731-BIB1025|term2731-cit-1026","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1002\/mus.21907","article-title":"Transplantation of olfactory ensheathing cells promotes axonal regeneration and functional recovery of peripheral nerve lesion in rats","volume":"43","author":"Gu\u00e9rout","year":"2011","journal-title":"Muscle and Nerve"},{"issue":"1","key":"10.1002\/term.2731-BIB0024|term2731-cit-0025","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1006\/exnr.2001.7774","article-title":"Transplantation of olfactory ensheathing cells stimulates the collateral sprouting from axotomized adult rat facial motoneurons","volume":"172","author":"Guntinas-Lichius","year":"2001","journal-title":"Experimental Neurology"},{"issue":"1","key":"10.1002\/term.2731-BIB0025|term2731-cit-0026","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.bbrc.2005.01.132","article-title":"Development of new inbred transgenic strains of rats with LacZ or GFP","volume":"329","author":"Inoue","year":"2005","journal-title":"Biochemical and Biophysical Research Communications"},{"issue":"5","key":"10.1002\/term.2731-BIB0026|term2731-cit-0027","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.injury.2010.12.030","article-title":"FDA approved guidance conduits and wraps for peripheral nerve injury: A review of materials and efficacy","volume":"43","author":"Kehoe","year":"2012","journal-title":"Injury"},{"issue":"1","key":"10.1002\/term.2731-BIB0027|term2731-cit-0028","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ejcb.2005.09.021","article-title":"Transdifferentiation of mesenchymal stem cells into schwann cell-like myelinating cells","volume":"85","author":"Keilhoff","year":"2006","journal-title":"European Journal of Cell Biology"},{"issue":"3","key":"10.1002\/term.2731-BIB0028|term2731-cit-0029","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1002\/jbm.a.32727","article-title":"PLGA conduit seeded with olfactory ensheathing cells for bridging sciatic nerve defect of rats","volume":"94","author":"Li","year":"2010","journal-title":"Journal of Biomedical Materials Research - Part A"},{"issue":"1","key":"10.1002\/term.2731-BIB0029|term2731-cit-0030","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1097\/SAP.0b013e31804d441c","article-title":"US Food and Drug Administration\/Conformit Europe-approved absorbable nerve conduits for clinical repair of peripheral and cranial nerves","volume":"60","author":"Meek","year":"2008","journal-title":"Annals of Plastic Surgery"},{"issue":"3","key":"10.1002\/term.2731-BIB0030|term2731-cit-0031","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1089\/ten.tea.2007.0107","article-title":"Cytocompatibility of a novel, longitudinally microstructured collagen scaffold intended for nerve tissue repair","volume":"15","author":"Mollers","year":"2009","journal-title":"Tissue Engineering. Part A"},{"key":"10.1002\/term.2731-BIB0031|term2731-cit-0032","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1159\/000338059","article-title":"Comparison of Schwann cells and olfactory ensheathing cells for peripheral nerve gap bridging","volume":"196","author":"Penna","year":"2012","journal-title":"Cells, Tissues, Organs"},{"issue":"1","key":"10.1002\/term.2731-BIB0032|term2731-cit-0033","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cne.20049","article-title":"Peripheral olfactory ensheathing cells reduce scar and cavity formation and promote regeneration after spinal cord injury","volume":"473","author":"Ramer","year":"2004","journal-title":"Journal of Comparative Neurology"},{"issue":"2","key":"10.1002\/term.2731-BIB0033|term2731-cit-0034","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1006\/exnr.1999.7315","article-title":"Nerve guides seeded with autologous Schwann cells improve nerve regeneration","volume":"161","author":"Rodr\u00edguez","year":"2000","journal-title":"Experimental Neurology"},{"issue":"1-2","key":"10.1002\/term.2731-BIB0034|term2731-cit-0035","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0006-8993(02)03930-6","article-title":"Rat Schwann cells in bioresorbable nerve guides to promote and accelerate axonal regeneration","volume":"963","author":"Schlosshauer","year":"2003","journal-title":"Brain Research"},{"issue":"1","key":"10.1002\/term.2731-BIB0035|term2731-cit-0036","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1146\/annurev.bioeng.5.011303.120731","article-title":"Neural tissue engineering: Strategies for repair and regeneration","volume":"5","author":"Schmidt","year":"2003","journal-title":"Annual Review of Biomedical Engineering"},{"issue":"1","key":"10.1002\/term.2731-BIB0036|term2731-cit-0037","first-page":"5","article-title":"Retrograde tracing and toe spreading after experimental autologous nerve transplantation and crush injury of the sciatic nerve: A descriptive methodological study","volume":"7","author":"Neerven","year":"2012","journal-title":"Journal of Brachial Plexus and Peripheral Nerve Injury"},{"issue":"5","key":"10.1002\/term.2731-BIB0037|term2731-cit-0038","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1097\/00001756-199904060-00035","article-title":"Olfactory bulb ensheathing cells enhance peripheral nerve regeneration","volume":"10","author":"Verdu","year":"1999","journal-title":"Neuroreport"},{"issue":"6","key":"10.1002\/term.2731-BIB0038|term2731-cit-0039","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/mus.21220","article-title":"Processed allografts and type I collagen conduits for repair of peripheral nerve gaps","volume":"39","author":"Whitlock","year":"2009","journal-title":"Muscle & Nerve"},{"issue":"8","key":"10.1002\/term.2731-BIB0039|term2731-cit-0040","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1177\/194589240501900115","article-title":"Endoscopic biopsy of human olfactory epithelium as a source of progenitor cells","volume":"19","author":"Winstead","year":"2005","journal-title":"American Journal of Rhinology"},{"issue":"1","key":"10.1002\/term.2731-BIB0040|term2731-cit-0041","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.expneurol.2010.08.034","article-title":"Olfactory ensheathing cells enhance Schwann cell-mediated anatomical and functional repair after sciatic nerve injury in adult rats","volume":"229","author":"You","year":"2011","journal-title":"Experimental Neurology"}],"container-title":["Journal of Tissue Engineering and Regenerative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fterm.2731","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/term.2731\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T16:44:49Z","timestamp":1720457089000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/term.2731"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,12]]},"references-count":41,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"URL":"https:\/\/doi.org\/10.1002\/term.2731","archive":["Portico"],"relation":{},"ISSN":["1932-6254"],"issn-type":[{"type":"print","value":"1932-6254"}],"subject":[],"published":{"date-parts":[[2018,9,12]]}}}