{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T22:10:21Z","timestamp":1792015821277,"version":"4.4.0"},"reference-count":75,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":3530,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Toxicol."],"published-print":{"date-parts":[[2006,6]]},"DOI":"10.1002\/tox.20180","type":"journal-article","created":{"date-parts":[[2006,4,27]],"date-time":"2006-04-27T18:21:33Z","timestamp":1146162093000},"page":"264-277","source":"Crossref","is-referenced-by-count":46,"title":["Comparative evaluation of genotoxicity of captan in amphibian larvae (Xenopus laevis andPleurodeles waltl) using the comet assay and the micronucleus test"],"prefix":"10.1002","volume":"21","author":[{"given":"F.","family":"Mouchet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Gauthier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Mailhes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Ferrier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Devaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006]]},"reference":[{"key":"10.1002\/tox.20180-BIB1","year":"2000","unstructured":"AFNOR. 2000. Association Fran\u00e7aise de Normalisation. NF T90-325. Qualit\u00e9 de l'eau\u2014evaluation de la g\u00e9notoxicit\u00e9 au moyen de larves d'amphibiens (Xenopus laevis, Pleurodeles waltl). 17 p."},{"key":"10.1002\/tox.20180-BIB2","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0027-5107(77)80020-1","volume":"42","author":"Ahmed","year":"1977","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB3","first-page":"35","volume":"22","author":"Anderson","year":"1974","journal-title":"Henry Ford Hosp Med J"},{"key":"10.1002\/tox.20180-BIB4","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/mutage\/13.1.67","volume":"13","author":"Anderson","year":"1998","journal-title":"Mutagenesis"},{"key":"10.1002\/tox.20180-BIB5","first-page":"392","volume":"50","author":"Anton","year":"1993","journal-title":"Bull Environ Contam Toxicol"},{"key":"10.1002\/tox.20180-BIB6","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0956-053X(01)00075-7","volume":"22","author":"Bekaert","year":"2002","journal-title":"Waste Manage"},{"key":"10.1002\/tox.20180-BIB7","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S1383-5718(98)00062-X","volume":"415","author":"Belpaeme","year":"1998","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB8","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1139\/f90-237","volume":"47","author":"Carrasco","year":"1990","journal-title":"Can J Fish Aquat Sci"},{"key":"10.1002\/tox.20180-BIB9","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0048-9697(02)00287-5","volume":"301","author":"Chenon","year":"2002","journal-title":"Sci Tot Environ"},{"key":"10.1002\/tox.20180-BIB10","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/(SICI)1098-2280(1997)29:3<277::AID-EM8>3.0.CO;2-9","volume":"29","author":"Clements","year":"1997","journal-title":"Environ Mol Mutagen"},{"key":"10.1002\/tox.20180-BIB11","first-page":"163","volume":"203","author":"Collins","year":"2002","journal-title":"Methods Mol Biol"},{"key":"10.1002\/tox.20180-BIB12","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/0048-3575(77)90047-5","volume":"7","author":"Couch","year":"1977","journal-title":"Pestic Biochem Physiol"},{"key":"10.1002\/tox.20180-BIB13","first-page":"65","volume":"75","author":"Das","year":"1986","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB14","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0141-1136(97)00105-0","volume":"46","author":"Devaux","year":"1998","journal-title":"Marine Environmental Research."},{"key":"10.1002\/tox.20180-BIB15","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1007\/s0012800111","volume":"65","author":"Djomo","year":"2000","journal-title":"Bull Environ Contam Toxicol"},{"key":"10.1002\/tox.20180-BIB16","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0165-1110(94)00013-3","volume":"339","author":"Fairbairn","year":"1995","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB17","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/mutage\/2.4.293","volume":"2","author":"Fernandez","year":"1987","journal-title":"Mutagenesis"},{"key":"10.1002\/tox.20180-BIB18","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/mutage\/4.1.17","volume":"4","author":"Fernandez","year":"1989","journal-title":"Mutagenesis"},{"key":"10.1002\/tox.20180-BIB19","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0165-1161(93)90010-W","volume":"292","author":"Fernandez","year":"1993","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB20","first-page":"507","volume":"35","author":"Ferrier","year":"1998","unstructured":", , . 1998. Genotoxicity tests in amphibians\u2014a review. Microscale testing in aquatic toxicology: advances, techniques and practice. 35: 507\u2013519."},{"key":"10.1002\/tox.20180-BIB21","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1080\/15287399209531636","volume":"36","author":"Fisher","year":"1992","journal-title":"J. Toxicol Environ Health"},{"key":"10.1002\/tox.20180-BIB22","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1006\/eesa.2001.2134","volume":"51","author":"Flammarion","year":"2002","journal-title":"Ecotoxicol Environ Saf"},{"key":"10.1002\/tox.20180-BIB23","first-page":"698","volume-title":"DNA repair and mutagenesis","author":"Friedberg","year":"1995","unstructured":", , . 1995. DNA repair and mutagenesis. American Society for Washington, DC: Microbiology Press. 698 p."},{"key":"10.1002\/tox.20180-BIB24","first-page":"97","volume":"91","author":"Galien","year":"1957","journal-title":"Bull Biol Fr Belg"},{"key":"10.1002\/tox.20180-BIB25","first-page":"53","volume":"14","author":"Gauthier","year":"1996","journal-title":"Int J Batrachol"},{"key":"10.1002\/tox.20180-BIB26","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.scitotenv.2003.10.014","volume":"323","author":"Gauthier","year":"2003","journal-title":"Sci Tot Environ"},{"key":"10.1002\/tox.20180-BIB27","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S1383-5718(01)00244-3","volume":"497","author":"Guecheva","year":"2001","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB28","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/em.2860080105","volume":"8","author":"Grinfeld","year":"1986","journal-title":"Environ Mutagen"},{"key":"10.1002\/tox.20180-BIB29","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/mutage\/18.1.45","volume":"18","author":"Hartmann","year":"2003","journal-title":"Mutagenesis"},{"key":"10.1002\/tox.20180-BIB30","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0165-1161(86)90058-0","volume":"164","author":"Jaylet","year":"1986","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB31","first-page":"151","volume":"2","author":"Jaylet","year":"1990","journal-title":"Aquat Sci"},{"key":"10.1002\/tox.20180-BIB32","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0300-483X(96)03316-1","volume":"109","author":"Jones","year":"1996","journal-title":"Toxicology"},{"key":"10.1002\/tox.20180-BIB33","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/em.2850100307","volume":"10","author":"Krauter","year":"1987","journal-title":"Environ Mol Mutagen"},{"key":"10.1002\/tox.20180-BIB34","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1023\/A:1016637809483","volume":"10","author":"Larno","year":"2001","journal-title":"Ecotoxicology"},{"key":"10.1002\/tox.20180-BIB35","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0166-445X(95)00016-W","volume":"33","author":"Liepelt","year":"1995","journal-title":"Aquat Toxicol"},{"key":"10.1002\/tox.20180-BIB36","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1080\/00031305.1978.10479236","volume":"32","author":"McGill","year":"1978","journal-title":"Am Statist"},{"key":"10.1002\/tox.20180-BIB37","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0027-5107(93)90207-V","volume":"288","author":"McKelvey","year":"1993","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB38","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/BF01688371","volume":"40","author":"Metcalfe","year":"1988","journal-title":"Bull Environ Contam Toxicol"},{"key":"10.1002\/tox.20180-BIB39","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0027-5107(97)00252-2","volume":"339","author":"Mitchelmore","year":"1998","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB40","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/tox.20080","volume":"20","author":"Mouchet","year":"2005a","journal-title":"Environ Toxicol"},{"key":"10.1002\/tox.20180-BIB41","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1080\/15287390590930234","volume":"68","author":"Mouchet","year":"2005b","journal-title":"J Toxicol Environ Health Part A"},{"key":"10.1002\/tox.20180-BIB42","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.scitotenv.2005.02.031","volume":"355","author":"Mouchet","year":"2006","journal-title":"Sci Tot Environ"},{"key":"10.1002\/tox.20180-BIB43","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S1383-5718(99)00164-3","volume":"464","author":"Moustacchi","year":"2000","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB44","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0166-445X(96)00016-1","volume":"35","author":"Nacci","year":"1996","journal-title":"Aquat Toxicol"},{"key":"10.1002\/tox.20180-BIB45","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1093\/jaoac\/76.2.381","volume":"76","author":"Newsome","year":"1993","journal-title":"J AOAC Int"},{"key":"10.1002\/tox.20180-BIB46","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0006-291X(83)90317-0","volume":"111","author":"Nose","year":"1983","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1002\/tox.20180-BIB47","first-page":"661","volume-title":"National Research Council. Drinking Water and Health","volume":"1","year":"1977","unstructured":"NRC. 1977. National Research Council. Drinking Water and Health, Vol. 1. Washington, DC: National Academic Press. p 661."},{"key":"10.1002\/tox.20180-BIB48","volume-title":"Normal tables of Xenopus laevis (Daudin)","author":"Nieuwkoop","year":"1956","unstructured":". 1956. Normal tables of Xenopus laevis (Daudin). Amerstedam, The Netherlands: North-Holland Pub."},{"key":"10.1002\/tox.20180-BIB49","doi-asserted-by":"crossref","first-page":"86","DOI":"10.2307\/3577587","volume":"122","author":"Olive","year":"1990","journal-title":"Radiat Res"},{"key":"10.1002\/tox.20180-BIB50","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0006-291X(84)90411-X","volume":"123","author":"\u00d6stling","year":"1984","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1002\/tox.20180-BIB51","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S1383-5718(00)00162-5","volume":"490","author":"Pavlica","year":"2001","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB52","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1159\/000213257","volume":"37","author":"Pacifici","year":"1991","journal-title":"Gerontology"},{"key":"10.1002\/tox.20180-BIB53","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0378-4347(98)00313-2","volume":"722","author":"Rojas","year":"1999","journal-title":"J Chromatogr B Biomed Sci Applied"},{"key":"10.1002\/tox.20180-BIB54","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/(SICI)1098-2280(1996)28:2<112::AID-EM7>3.0.CO;2-H","volume":"28","author":"Ralph","year":"1996","journal-title":"Environ Mol Mutagen"},{"key":"10.1002\/tox.20180-BIB55","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S1383-5718(98)00024-2","volume":"413","author":"Ralph","year":"1998a","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB56","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/(SICI)1098-2280(1998)31:4<374::AID-EM10>3.0.CO;2-9","volume":"31","author":"Ralph","year":"1998b","journal-title":"Environ Mol Mutagen"},{"key":"10.1002\/tox.20180-BIB57","author":"Simmon","year":"1977","journal-title":"EPA Report"},{"key":"10.1002\/tox.20180-BIB58","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/0014-4827(88)90265-0","volume":"175","author":"Singh","year":"1988","journal-title":"Exp Cell Res"},{"key":"10.1002\/tox.20180-BIB59","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/0014-4827(89)90344-3","volume":"184","author":"Singh","year":"1989","journal-title":"Exp Cell Res"},{"key":"10.1002\/tox.20180-BIB60","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0165-1161(91)90008-V","volume":"252","author":"Singh","year":"1991","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB61","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/em.2850200208","volume":"20","author":"Snyder","year":"1992","journal-title":"Environ Mol Mutagen"},{"key":"10.1002\/tox.20180-BIB62","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/em.2860070304","volume":"7","author":"Snyder","year":"1985","journal-title":"Environ Mutagen"},{"key":"10.1002\/tox.20180-BIB63","series-title":"DNA repair pr","first-page":"203","volume-title":"Methods in molecular biology","volume":"113","author":"Speit","year":"1999","unstructured":". 1999. The comet assay (single-cell gel test)\u2014a sensitive genotoxicity test for the detection of DNA damage and repair. In: editor. Methods in molecular biology, Vol. 113, DNA repair protocols: eucaryotic systems. Totowa, NJ: Humana Press. p 203\u2013212."},{"key":"10.1002\/tox.20180-BIB64","year":"1981","unstructured":"SCC. 1981. Stauffer Chemical Company. The association of captan with mouse and rat deoxyribonucleic acid. Report No. T-10435."},{"key":"10.1002\/tox.20180-BIB65","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1248\/bpb.20.271","volume":"20","author":"Suzuki","year":"1997","journal-title":"Boil Pharm Bull"},{"key":"10.1002\/tox.20180-BIB66","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.tox.2004.06.025","volume":"204","author":"Suzuki","year":"2004","journal-title":"Toxicology"},{"key":"10.1002\/tox.20180-BIB67","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/S0006-291X(76)80100-3","volume":"72","author":"Swenberg","year":"1976","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1002\/tox.20180-BIB68","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/(SICI)1098-2280(2000)35:3<206::AID-EM8>3.0.CO;2-J","volume":"35","author":"Tice","year":"2000","journal-title":"Environ Mol Mutagen"},{"key":"10.1002\/tox.20180-BIB69","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1093\/humrep\/17.7.1856","volume":"17","author":"Tomsu","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1002\/tox.20180-BIB70","year":"1999","unstructured":"U.S. EPA. 1999. Environmental Protection Agency (U.S.). Registration eligibility decision (RED): captan. microfiche: PB2000-101656, EPA\/738\/F-."},{"key":"10.1002\/tox.20180-BIB71","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4757-2440-0","volume-title":"The nature of statistical learning theory","author":"Vapnik","year":"1995","unstructured":"1995. The nature of statistical learning theory. New York: Springer Ed."},{"key":"10.1002\/tox.20180-BIB72","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0027-5107(97)00268-6","volume":"399","author":"Wilson","year":"1998","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB73","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.mrfmmm.2004.06.014","volume":"552","author":"Winter","year":"2004","journal-title":"Mutat Res"},{"key":"10.1002\/tox.20180-BIB74","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1021\/jf60207a004","volume":"24","author":"Wolfe","year":"1976","journal-title":"J Agric Food Chem"},{"key":"10.1002\/tox.20180-BIB75","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/978-1-4615-3808-0_19","volume-title":"Mechanisms of environmental mutagenesis-carcinogenesis","author":"Zoll","year":"1990","unstructured":", . 1990. Use of aquatic animals for monitoring genotoxicity in unconcentrated water samples. In: editor. Mechanisms of environmental mutagenesis-carcinogenesis. New York: Plenum Press. p 233\u2013244."}],"container-title":["Environmental Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Ftox.20180","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/tox.20180","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T18:09:56Z","timestamp":1736359796000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/tox.20180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":75,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,6]]}},"URL":"https:\/\/doi.org\/10.1002\/tox.20180","relation":{},"ISSN":["1520-4081","1522-7278"],"issn-type":[{"value":"1520-4081","type":"print"},{"value":"1522-7278","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}