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The FT\u2010IR spectra of the lead\u2010exposed bones show significant alteration in the biochemical constituents. The XRD analysis showed a decrease in crystallinity due to lead exposure. Further, the Ca, Mg, and P contents of the lead\u2010exposed bones were less than those of the control group, and there was an increase in the mineral contents of the bones after DMSA treatment. In conclusion, the present study suggests that the subchronic lead exposure results in severe loss of bone minerals. The overall decrease in the FT\u2010IR band intensity of Pb\u2010exposed bones relative to the control indicates a decrease in the biochemical constituents like proteins and lipids. The increase in the band intensity after treatment with chelating agent DMSA indicates increased biochemical constituents, showing that the subchronic effects of lead can be reversed by DMSA. The amide I bands observed at 1654 cm<jats:sup>\u22121<\/jats:sup>in the present study suggest that the protein is dominated by \u03b1\u2010helical structure. \u00a9 2009 Wiley Periodicals, Inc. Environ Toxicol, 2010.<\/jats:p>","DOI":"10.1002\/tox.20475","type":"journal-article","created":{"date-parts":[[2009,2,13]],"date-time":"2009-02-13T18:21:46Z","timestamp":1234549306000},"page":"61-67","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The study of the changes in the biochemical and mineral contents of bones of<i>Catla catla<\/i>due to lead intoxication"],"prefix":"10.1002","volume":"25","author":[{"given":"PL. 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