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Whether or not such BPA analogues are safe substitutes, however, remains largely unknown. Here, we investigated the potential of bisphenol B (BPB), bisphenol E (BPE), bisphenol F (BPF), bisphenol S (BPS), and 4\u2010cumylphenol (4\u2010CP) to affect lipid and hormone levels in 3 T3\u2010L1 cells. We found that BPB, BPE, BPF, BPS, and 4\u2010CP all affected lipid accumulation and leptin levels to the same extent and potencies as BPA. Based on these and other results, we conclude that these BPA analogues and 4\u2010CP most likely will elicit similar effects on adipocytes as BPA. Using them to substitute BPA in products should be done with caution.<\/jats:p>","DOI":"10.1002\/tox.22889","type":"journal-article","created":{"date-parts":[[2019,12,10]],"date-time":"2019-12-10T09:30:54Z","timestamp":1575970254000},"page":"543-552","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Bisphenols B, E, F, and S and 4\u2010cumylphenol induce lipid accumulation in mouse adipocytes similarly to bisphenol A"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7962-9159","authenticated-orcid":false,"given":"Cecilie N.","family":"Ramskov Tetzlaff","sequence":"first","affiliation":[{"name":"Division of Diet, Disease Prevention and Toxicology National Food Institute, Technical University of Denmark  Lyngby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terje","family":"Svingen","sequence":"additional","affiliation":[{"name":"Division of Diet, Disease Prevention and Toxicology National Food Institute, Technical University of Denmark  Lyngby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne M.","family":"Vinggaard","sequence":"additional","affiliation":[{"name":"Division of Diet, Disease Prevention and Toxicology National Food Institute, Technical University of Denmark  Lyngby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna K.","family":"Rosenmai","sequence":"additional","affiliation":[{"name":"Division of Diet, Disease Prevention and Toxicology National Food Institute, Technical University of Denmark  Lyngby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Taxvig","sequence":"additional","affiliation":[{"name":"Division of Diet, Disease Prevention and Toxicology National Food Institute, Technical University of Denmark  Lyngby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","unstructured":"Heindel J. J. Jobling S. Kidd K. A.&Zoeller R. T.State of the Science of Endocrine Disrupting Chemicals \u2010 2012. (2013). doi:https:\/\/doi.org\/10.1016\/j.toxlet.2012.03.020","DOI":"10.1016\/j.toxlet.2012.03.020"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2013.05.028"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2012.01.001"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2011.04.005"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2007.07.010"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.10753"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2009.02.018"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfi088"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2012.03.021"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.5551\/jat.E486"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1205548"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/em.21803"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-1989"},{"key":"e_1_2_8_15_1","unstructured":"Government of Canada. ARCHIVED \u2014 Canada Gazette \u2013 Order Amending Schedule I to the Hazardous Products Act (bisphenol A). (2010).http:\/\/www.gazette.gc.ca\/rp-pr\/p2\/2010\/2010-03-31\/html\/sor-dors53-eng.html. Accessed July 13 2014."},{"key":"e_1_2_8_16_1","first-page":"29","article-title":"The European Commission of 28 January 2011 amending directive 2002\/72\/EC as regards the restriction of use of Bisphenol A in plastic infant feeding bottles","volume":"54","year":"2011","journal-title":"Off. J. Eur. 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