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We used mass spectrometry on chemically digested liquid samples from five fish species from Turag\u2010Tongi\u2010Balu to estimate the concentrations of 10 elements (Cr, Mn, Ni, Cu, Zn, As, Se, Cd, Fe, and Pb). Except <jats:italic>M. vittatus<\/jats:italic>, the mean concentrations of Cd, Mn, Pb, and Se exceeded the Food Safety Guideline (FSG) value in all fish species. Among the species studied, <jats:italic>L. rohita<\/jats:italic>, <jats:italic>C. punctata<\/jats:italic>, <jats:italic>C. batrachus<\/jats:italic>, <jats:italic>H. fossilis<\/jats:italic>, and <jats:italic>M. vittatus<\/jats:italic> exhibited higher Mn concentrations surpassing the FSG threshold, thus elevating the non\u2010carcinogenic risk across all species. There were statistically significant differences (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) in the mean concentrations of heavy metals among fish species. The Target Hazard Quotient (THQ) value of Mn poses a significant non\u2010carcinogenic risk to human health, while the hazard of other metals is negligible. Except for <jats:italic>M. vittus<\/jats:italic>, the Hazard Index value (HI\u2009\u2265\u20091) revealed the risk that all metals exceed the limit and pose a threat to human health. Cd, As, and Ni metals pose a significant carcinogenic risk to human health from the consumption of fish samples, which is a particularly alarming target cancer risk (TCR). In conclusion, regular dietary consumption of fish from this polluted ecosystem of the Turag\u2010Tongi\u2010Balu River channel's Kamarpara site poses a significant health risk and is indicated as cancer. 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